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Non-destructive biomarkers can reveal effects of the association of microplastics and pharmaceuticals or personal care products

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Autor(es):
da Silva, Leticia Fernanda ; Nobre, Caio Rodrigues ; Moreno, Beatriz Barbosa ; Seabra Pereira, Camilo Dias ; de Souza Abessa, Denis Moledo ; Choueri, Rodrigo Brasil ; Gusso-Choueri, Paloma Kachel ; Cesar, Augusto
Número total de Autores: 8
Tipo de documento: Artigo Científico
Fonte: Marine Pollution Bulletin; v. 177, p. 10-pg., 2022-03-04.
Resumo

Methods to assess the effects of contaminants on marine organisms typically involve euthanasia to obtain samples, but less invasive techniques may be more appropriate for working with threatened species. In this study, were assessed the biological responses of crabs exposed to microplastics and contaminants of emerging concern. Biochemical and cellular effects (lipid pemxidation, DNA damage, cholinesterase activity, and lysosomal membrane stability) in hemolymph were analyzed in a kinetic study, at 3 and 7 days, in U. cordatus exposed to microplastics spiked with Triclosan (TCS) or 17 alpha-Ethynylestradiol (EE2). The results showed that the contaminants were produced toxic effects in the crabs exposed either to the microplastics alone (oxidative stress, genotoxicity, and neurotoxicity), or to micmplastics with TCS or EE2 adsorbed (neumtoxic and cytotoxic). The present study showed the responsiveness of non-lethal analyzes to understanding the biological effects of combined exposure to micmplastics and chemical pollution. (AU)

Processo FAPESP: 17/07353-7 - Avaliação dos efeitos da acidificação dos oceanos sobre a biodisponibilidade de poluentes emergentes - acidocean
Beneficiário:Augusto Cesar
Modalidade de apoio: Auxílio à Pesquisa - Regular
Processo FAPESP: 17/04970-5 - Relações entre concentrações de metais no sedimento, bioacumulação e respostas tóxicas em p. vivipara: subsídios para avaliação de risco ambiental
Beneficiário:Paloma Kachel Gusso Choueri
Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 17/12193-9 - Avaliação do risco ambiental da interação de microplástico, fármaco e antimicrobiano: uma abordagem ecotoxicológica
Beneficiário:Caio Rodrigues Nobre
Modalidade de apoio: Bolsas no Brasil - Doutorado