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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Ultra-processed food consumption and type 2 diabetes incidence: A prospective cohort study

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Autor(es):
Levy, Renata B. [1, 2, 3] ; Rauber, Fernanda [4, 1, 2] ; Chang, Kiara [3] ; Louzada, Maria Laura da C. [4, 2] ; Monteiro, Carlos A. [4, 2] ; Millett, Christopher [1, 2, 3] ; Vamos, Eszter P. [3]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Sch Med, Dept Prevent Med, BR-01246903 Sao Paulo - Brazil
[2] Univ Sao Paulo, Ctr Epidemiol Res Nutr & Hlth, BR-01246904 Sao Paulo - Brazil
[3] Imperial Coll London, Sch Publ Hlth, Publ Hlth Policy Evaluat Unit, London W6 8RP - England
[4] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, BR-01246904 Sao Paulo - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: Clinical Nutrition; v. 40, n. 5, p. 3608-3614, MAY 2021.
Citações Web of Science: 3
Resumo

Background: Ultra-processed foods account for more than 50% of daily calories consumed in several high-income countries, with sales of ultra-processed foods soaring globally, especially in middle-income countries. The objective of this study is to investigate the association between ultra-processed food (UPF) consumption and risk of type 2 diabetes (T2D) in a UK-based prospective cohort study. Methods: Participants of the UK Biobank (2007-2019) aged 40-69 years without diabetes at recruitment who provided 24-h dietary recall and follow-up data were included. UPFs were defined using the NOVA food classification. Multivariable Cox proportional hazards regression models were used to evaluate the association between UPF consumption and the risk of T2D adjusting for socio-demographic, anthropometric and lifestyle characteristics. Results: A total of 21,730 participants with a mean age of 55.8 years and mean UPF intake of 22.1% at baseline were included. During a mean follow-up of 5.4 years (116,956 person-years), 305 incident T2D cases were identified. In the fully adjusted model, compared with the group in the lowest quartile of UPF intake, the hazard ratio for T2D was 1.44, 1.04-2.02 in the group with the highest quartile of UPF consumption. A gradient of elevated risk of T2D associated with increasing quartiles of UPF intake was consistently observed (p value for trend < 0.028). A significantly increased risk of T2D was observed per 10 percentage points increment in UPF consumption ({[}adjusted HR]: 1.12, 95% confidence interval {[}CI]: 1.04-1.20). Conclusions: Our findings demonstrate that a diet high in UPFs is associated with a clinically important increased risk of T2D. Identifying and implementing effective public health actions to reduce UPF consumption in the UK and globally are urgently required. (c) 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved. (AU)

Processo FAPESP: 18/19820-1 - Consumo de alimentos ultraprocessados e obesidade na coorte Biobank do Reino Unido
Beneficiário:Fernanda Rauber
Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado
Processo FAPESP: 16/14302-7 - Consumo de alimentos ultraprocessados e indicadores de qualidade nutricional da dieta na Austrália
Beneficiário:Fernanda Rauber
Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 18/26660-0 - Consumo de alimentos ultraprocessados e incidência de diabetes na população inglesa: coorte Biobank
Beneficiário:Renata Bertazzi Levy
Modalidade de apoio: Bolsas no Exterior - Pesquisa
Processo FAPESP: 15/14900-9 - Consumo de alimentos ultraprocessados, perfil nutricional da dieta e obesidade em sete países
Beneficiário:Carlos Augusto Monteiro
Modalidade de apoio: Auxílio à Pesquisa - Temático