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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Performance of functionality measures and phase angle in women exposed to chemotherapy for early breast cancer

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da Silva, Bruna Ramos [1] ; Mialich, Mirele S. [1] ; Cruz, Loris P. [2] ; Rufato, Sarah [1] ; Gozzo, Thais [2] ; Jordao, Alceu A. [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Hlth Sci, Bandeirantes Ave 3900, BR-14049900 Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Nursing Sch Ribeirao Preto, Ribeirao Preto, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: CLINICAL NUTRITION ESPEN; v. 42, p. 105-116, APR 2021.
Citações Web of Science: 0

Purpose: The study aimed to analyze the influence of chemotherapy on nutritional status and the phase angle (PhA) as nutritional indicator for breast cancer women undergoing chemotherapy. Methods: A prospective study was performed. Women who were starting chemotherapy with no previous chemotherapy treatment were recruited. Quality of life (QoL) was collected using the EORTC QLQBR23 questionnaire. Bioelectrical impedance analysis, performance tests, and blood sample to albumin analyzes were collected at 2-time points: diagnosis (T0) and after 1 month of completion of therapy (T1). Mean, standard deviation, linear regression, and ANOVA in R were used to explore the results. Results: 61 women were included. We did not find any changes in body composition. However, PhA, nutritional risk index (NRI), gait speed (GS), and handgrip strength (HGS) had expressive changes (p < 0.001). 75.4% of women had PhA values below the cut-off point of 5.6 degrees, and the group that had a lower average of PhA also expressed low NRI. PhA was a nutritional status marker and its values were influenced by changes in NRI (p < 0.05). Conclusion: We have found supporting evidence for chemotherapy treatment resulting in worsening of prognostic factors such as PhA, and yet PhA was related to no nutritional risk. Besides a higher prevalence of obesity, 80% of the sample showed some nutritional risk level, implying the possibility of a subnotification candidate who might benefit, for instance, from nutritional intervention in obesity groups. Further investigation about this theme may improve health measures for the prevention and screening of disease among breast cancer. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights (AU)

Processo FAPESP: 17/07963-0 - Avaliação do perfil metabólico, oxidativo e antropométrico em mulheres com Câncer de Mama
Beneficiário:Bruna Ramos da Silva
Linha de fomento: Bolsas no Brasil - Doutorado Direto