| Texto completo | |
| Autor(es): |
Número total de Autores: 3
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| Afiliação do(s) autor(es): | [1] Inst Butantan, Ecol & Evolut Lab, Ave Dr Vital Brasil 1500, BR-05503900 Sao Paulo - Brazil
Número total de Afiliações: 1
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| Tipo de documento: | Artigo Científico |
| Fonte: | Toxicon; v. 146, p. 124-128, MAY 2018. |
| Citações Web of Science: | 0 |
| Resumo | |
beta-Defensins are cationic antimicrobial peptides showing little sequence similarity but highly conserved tertiary structure stabilized by a six-cysteines-motif. Using a PCR approach, we described beta-defensin sequences with two exons in three species of Colubridae snakes with high sequence similarity between them. The deduced amino acid sequence presented the characteristics of beta-defensin family. The phylogenetic analysis using beta-defensin coding sequences of different snakes grouped them in two main branches: genes organized in three or two exons. (C) 2018 Elsevier Ltd. All rights reserved. (AU) | |
| Processo FAPESP: | 15/00003-5 - Genes de toxinas de venenos e b-defensinas de serpentes |
| Beneficiário: | Nancy Oguiura |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |