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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Influence of menopausal status on the main contributors of muscle quality

Texto completo
Autor(es):
Carvalho, L. P. [1, 2, 3] ; Borghi-Silva, A. [1] ; Dupontgand, S. [2, 3] ; Di Thommazo-Luporini, L. [1] ; Mendes, R. G. [1] ; Aubertin-Leheudre, M. [2, 3]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Carlos, Dept Phys Therapy, Sao Carlos, SP - Brazil
[2] Univ Quebec Montreal, Dept Phys Act Sci, Montreal, PQ - Canada
[3] Ctr Rech Inst Univ Geriatrie Montreal, Montreal, PQ - Canada
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: CLIMACTERIC; v. 21, n. 3, p. 298-302, 2018.
Citações Web of Science: 0
Resumo

Background: Muscle quality is a strong independent predictor of physical function. Body mass and fatness, muscle mass and cardiorespiratory fitness are known to influence muscle quality.Objective: To identify the contributors of muscle quality in young and postmenopausal women and whether hormone replacement therapy (HT) could influence this relationship at the age of menopause.Methods: Fifty-four postmenopausal women, 27 not on HT (PMW) and 27 on HT (PMW-HT), and 33 young women (YW) were evaluated for (1) body composition (body mass index, BMI), total fat mass (FM, %), appendicular lean mass (ALM, in kg and %), and appendicular skeletal mass index (ASMI=ALM/height(2) in kg/m(2)); (2) absolute peak oxygen uptake (VO2peak, in ml/min) and relative peak oxygen uptake (VO2peakRel in ml/kg/min); and (3) absolute isometric knee extension strength (iKES in kg) and relative isometric knee extension strength (iKES/BMI and iKES/ALM).Results: YW, PMW and PMW-HT had similar BMI (32.110.2, 27.3 +/- 4.7 and 26.7 +/- 4kg/m(2)) and FM (39.8 +/- 10.0, 39.8 +/- 7.3 and 39.9 +/- 7.1%), respectively. Correlations were found between iKES/BMI index and FM (r=-0.52), ALM (r=0.32) and VO2peak (r=0.31). Regression analysis demonstrated that, in YW, total amount of variance in iKES/BMI was mostly explained by ALM (42%), whereas, in PMW and PMW-HT, it was cumulatively explained by FM along with VO2peakRel (34 and 46%, respectively).Conclusion: The main contributors of muscle quality differ between young and postmenopausal women and HT does not seem to influence this relationship. (AU)

Processo FAPESP: 13/15681-3 - Relacionamento entre estrutura e função muscular periférica, inflamação sistêmica e regulação autonômica em adultos obesos
Beneficiário:Lívia Pinheiro Carvalho
Linha de fomento: Bolsas no Brasil - Doutorado Direto
Processo FAPESP: 15/12751-6 - Efeito de uma intervenção combinada de um suplemento nutricional associado ao treinamento de caminhada na saúde de homens idosos obesos-sarcopênicos: a influência na composição corporal, composição e função musculares e perfil metabólico
Beneficiário:Lívia Pinheiro Carvalho
Linha de fomento: Bolsas no Exterior - Estágio de Pesquisa - Doutorado Direto