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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The effect of mate tea (Ilex paraguariensis) on metabolic and inflammatory parameters in high-fat diet-fed Wistar rats

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Author(s):
Borges, Maria Carolina [1] ; Ramirez Vinolo, Marco Aurelio [2] ; Nakajima, Karina [3] ; De Castro, Inar Alvesde [4] ; Markowicz Bastos, Deborah Helena [1] ; Borelli, Primavera [3] ; Fock, Ricardo Ambrosio [3] ; Tirapegui, Julio [4] ; Curi, Rui [2] ; Rogero, Marcelo Macedo [1]
Total Authors: 10
Affiliation:
[1] Univ Sao Paulo, Sch Publ Hlth, Dept Nutr, BR-01246904 Sao Paulo - Brazil
[2] Univ Sao Paulo, Inst Biomed Sci, Dept Physiol & Biophys, BR-05508000 Sao Paulo - Brazil
[3] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Clin & Toxicol Anal, BR-05508000 Sao Paulo - Brazil
[4] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Food & Expt Nutr, BR-05508000 Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION; v. 64, n. 5, p. 561-569, AUG 2013.
Web of Science Citations: 14
Abstract

This study investigated the effects of mate tea (Ilex paraguariensis) aqueous extract consumption on metabolic indicators and inflammatory response of peritoneal macrophages in rats fed a high-fat diet (HFD). Male Wistar rats were fed a control diet or a HFD for 12 weeks. At the end of this period, rats received, or not, daily doses of yerba mate for 4 weeks. The consumption of yerba mate promoted weight loss, attenuated the HFD-detrimental effects on adiposity and insulin sensitivity and decreased blood levels of the inflammatory biomarkers (p < 0.05). Concerning peritoneal macrophages, mate tea consumption decreased the production of interleukin (IL)-6, but did not influence the production of IL-1 beta, tumour necrosis factor-a and nitric oxide; cytokine mRNA expression; or the activation of the nuclear factor-kappa B signalling pathway. In summary, the consumption of mate tea had no consistent effect in the inflammatory response of peritoneal macrophages, but reduced cardiometabolic risk markers. (AU)

FAPESP's process: 09/02371-0 - The effect of yerba mate (Ilex paraguariensis) aqueous extract ingestion on nuclear factor kappa B signaling pathway in peritoneal macrophages of rats fed a high-fat diet
Grantee:Maria Carolina Borges
Support type: Scholarships in Brazil - Master