An evaluative review on Stryphnodendron adstringens extract composition: Current and future perspectives on extraction and application

The search for natural products as an alternative to synthetic products has increased. This trend is mainly due to the health concerns of people searching for a better quality of life. In this context, obtaining bioactive compounds from vegetable matrices is a promising strategy for industrial applications like pharmaceuticals and food. Stryphnodendron adstringens (Mart.) Coville (popularly known as Barbatimao in Brazil) is a tree used in folk medicine due to its anti-inflammatory, analgesic, antiseptic, and wound healing properties. Its barks and leaves present a wide range of bioactive compounds, mainly phenolic acids, flavonoids, and tannins. The extraction of such compounds can be performed using various methods. However, specific knowledge to select the technique to obtain and concentrate the compounds is essential to obtain an extract of high purity. In addition, there is a current necessity to describe the whole production chain as sustainable. Therefore, this review aims to bring updated information on current research with Barbatimao extracts. The biological activities of the extracts are related to the extract composition. Additionally, the extraction techniques used for different parts of Barbatimao, as well as their chemical composition, are also discussed. Finally, future perspectives are provided to demonstrate the current gaps in scientific research with Barbatimao and encourage future investigations to open possibilities for the use of this species. (AU)