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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Implants with hydrophilic surfaces equalize the osseointegration of implants in normo- and hyperglycaemic rats

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Felipe Eduardo Pinotti [1] ; Mauricio Andrés Tinajero Aron [2] ; Guilherme José Pimentel Lopes de Oliveira [3] ; Elcio Marcantonio Junior [4] ; Rosemary Adriana Chiérici Marcantonio [5]
Total Authors: 5
[1] São Paulo State University. School of Dentistry - Brasil
[2] San Francisco de Quito University - Equador
[3] Universidade Federal de Uberlândia. School of Dentistry - Brasil
[4] São Paulo State University. School of Dentistry - Brasil
[5] São Paulo State University. School of Dentistry - Brasil
Total Affiliations: 5
Document type: Journal article
Source: Brazilian Dental Journal; v. 33, n. 6, p. 71-77, 2022-12-05.

Abstract The purpose of this study was to evaluate the effect of a surface modified by blasting and acid attack and maintained in an isotonic solution compared to a machined surface on osseointegration in normo- and hyperglycaemic animals. Sixty-four animals were allocated into 4 groups with 16 animals each, and they were subdivided into two experimental periods (15 and 45 days), with 8 animals in each group. The groups were divided according to the type of implant that was installed in the animals' tibia and the animals’ systemic condition: CM - Machined implants placed in Healthy animals; CH - Hydrophilic implants placed in Healthy animals, HM - Machined implants placed in animals with hyperglycaemia; HH- Hydrophilic implants installed in animals with hyperglycaemia. The following analyses were performed: biomechanical (removal torque), microtomographic (evaluation of the bone volume around the implants- BV/TV), and histomorphometric (evaluation of bone-implant contact BIC% and of the bone formation area between the threads BBT%). It was found that the implants with hydrophilic surfaces presented higher removal torques and quantities of BV/TV% and higher BIC% and BBT% values in normo- and hyperglycaemic animals. The results of this study indicated that the hydrophilic surface accelerates the osseointegration process (~ 15% BIC/BBT at 15-day period), especially in animals with hyperglycaemia. The hydrophilic surface equaled the osseointegration between normo- and hyperglycaemic animals, reversing the negative potential of hyperglycaemia on the osseointegration process. (AU)

FAPESP's process: 18/01610-0 - Evaluation of osseointegration of ACQUA implants in rats with systemic involvement
Grantee:Felipe Eduardo Pinotti
Support Opportunities: Scholarships in Brazil - Doctorate