Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

enefits of Home-Based Exercise Training Following Critical SARS-CoV-2 Infection: A Case Repor

Full text
Author(s):
Longobardi, Igor [1] ; do Prado, Danilo Marcelo Leite [1] ; Goessler, Karla Fabiana [1] ; de Oliveira Junior, Gersiel Nascimento [1] ; de Andrade, Danieli Castro Oliveira [2] ; Gualano, Bruno [2, 1] ; Roschel, Hamilton [2, 1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Fac Med, Sch Phys Educ & Sport, Appl Physiol & Nutr Res Grp, Sao Paulo - Brazil
[2] Univ Sao Paulo, Fac Med, Hosp Clin, Rheumatol Div, Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: FRONTIERS IN SPORTS AND ACTIVE LIVING; v. 3, JAN 11 2022.
Web of Science Citations: 0
Abstract

In the current scenario, in which an elevated number of COVID-19 survivors present with severe physical deconditioning, exercise intolerance, persistent symptoms, and other post-acute consequences, effective rehabilitation strategies are of utmost relevance. In this study, we report for the first time the effect of home-based exercise training (HBET) in a survivor patient from critical COVID-19 illness. A 67-year-old woman who had critical COVID-19 disease {[}71 days of hospitalization, of which 49 days were in the intensive care unit (ICU) with invasive mechanical ventilation due to respiratory failure] underwent a 10-week HBET aiming to recovering overall physical condition. Before and after the intervention, we assessed cardiopulmonary parameters, skeletal muscle strength and functionality, fatigue severity, and self-reported persistent symptoms. At baseline (3 months after discharge), she presented with severe impairment in cardiorespiratory functional capacity (<50% age predicted VO2peak). After the intervention, remarkable improvements in VO2peak (from 10.61 to 15.48 mL center dot kg(-1)center dot min(-1), Delta: 45.9%), oxygen uptake efficiency slope (OUES; from 1.0 to 1.3 L center dot min(-1), Delta: 30.1%), HR/VO2 slope (from 92 to 52 bpm center dot L-1, Delta: -43.5%), the lowest VE/VCO2 ratio (from 35.4 to 32.9 L center dot min(-1), Delta: -7.1%), and exertional dyspnea were observed. In addition, handgrip strength (from 22 to 27 kg, Delta: 22.7%), 30-s Sit-to-Stand (30-STS; from 14 to 16 repetitions, Delta:14.3%), Timed-Up-and-Go (TUG; from 8.25 to 7.01 s, Delta: -15%) performance and post-COVID functional status (PCFS) score (from 4 to 2) were also improved from baseline to post-intervention. Self-reported persistent symptoms were also improved, and Fatigue Severity Scale (FSS) score decreased (from 4 to 2.7) from baseline to post-intervention. This is the first evidence that a semi-supervised, HBET program may be safe and potentially effective in improving cardiorespiratory and physical functionality in COVID-19 survivors. Controlled studies are warranted to confirm these findings. (AU)

FAPESP's process: 20/07540-4 - Effects of exercise training associated with protein supplementation on bone parameters in older people with sarcopenic obesity under caloric restriction: a randomized controlled clinical trial
Grantee:Gersiel Nascimento de Oliveira Júnior
Support type: Scholarships in Brazil - Doctorate