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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

omparative Characterization of Mitogenomes From Five Orders of Cestodes (Eucestoda: Tapeworms

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Trevisan, Bruna [1] ; Jacob Machado, Denis [2] ; Lahr, Daniel J. G. [1] ; Marques, Fernando P. L. [1]
Total Authors: 4
[1] Univ Sao Paulo, Inst Biosci, Dept Zool, Sao Paulo - Brazil
[2] Univ North Carolina Charlotte, Coll Comp & Informat, Dept Bioinformat & Genom, Charlotte, NC - USA
Total Affiliations: 2
Document type: Journal article
Source: FRONTIERS IN GENETICS; v. 12, DEC 22 2021.
Web of Science Citations: 0

The recognized potential of using mitogenomics in phylogenetics and the more accessible use of high-throughput sequencing (HTS) offer an opportunity to investigate groups of neglected organisms. Here, we leveraged HTS to execute the most comprehensive documentation of mitogenomes for cestodes based on the number of terminals sequenced. We adopted modern approaches to obtain the complete mitogenome sequences of 86 specimens representing five orders of cestodes (three reported for the first time: Phyllobothriidea, ``Tetraphyllidea{''} and Trypanorhyncha). These complete mitogenomes represent an increase of 41% of the mitogenomes available for cestodes (61-147) and an addition of 33% in the representativeness of the cestode orders. The complete mitochondrial genomes are conserved, circular, encoded in the same strand, and transcribed in the same direction, following the pattern observed previously for tapeworms. Their length varies from 13,369 to 13,795 bp, containing 36 genes in total. Except for the Trypanorhyncha specimen, the gene order of the other four cestode orders sequenced here suggests that it could be a synapomorphy for the acetabulate group (with a reversion for taenids). Our results also suggest that no single gene can tell all the evolutionary history contained in the mitogenome. Therefore, cestodes phylogenies based on a single mitochondrial marker may fail to capture their evolutionary history. We predict that such phylogenies would be improved if conducted under a total evidence framework. The characterization of the new mitochondrial genomes is the first step to provide a valuable resource for future studies on the evolutionary relationships of these groups of parasites. (AU)

FAPESP's process: 18/03534-0 - Systematics of Rhinebothrium Linton, 1890 and the composition of the Rhinebothriidae Euzet, 1953 (Platyhelminthes: Cestoda): a new approach for an old problem in cestodes systematics
Grantee:Fernando Portella de Luna Marques
Support Opportunities: Regular Research Grants
FAPESP's process: 17/11063-4 - Systematic of Rhinebothrium Linton, 1890 and composition of Rhinebothriidae Euzet, 1953 (Platyhelminthes: Cestoda)
Grantee:Bruna Trevisan Souza Szucko
Support Opportunities: Scholarships in Brazil - Doctorate