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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A better quality of maternal dietary fat reduces the chance of large-for-gestational-age infants: A prospective cohort study

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de Lima, Maria Carolina [1] ; Santos, Izabela da Silva [2] ; Crivellenti, Livia Castro [1] ; Sartorelli, Daniela Saes [3]
Total Authors: 4
[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Grad Program Publ Hlth, Sao Paulo - Brazil
[2] Univ Sao Paulo, Ribeirao Preto Med Sch, Grad Program Nutr & Metab, Sao Paulo - Brazil
[3] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Social Med, Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: NUTRITION; v. 91-92, NOV-DEC 2021.
Web of Science Citations: 0

Objectives: We sought to investigate the relationship between the usual intake of fatty acids and indices of dietary fat quality in pregnant women and the birth-weight categories of their newborns. Methods: This prospective cohort study was conducted with 734 mother-infant pairs in Brazil. Dietary intake was estimated through 24-h dietary recalls. Secondary data on birth weight, sex of the newborn, and pregnancy duration were obtained. The relationship of fatty acids and indices with birth-weight categories were investigated using logistic regression models adjusted for confounding factors. We considered P values < 0.05 significant. Results: The median (interquartile range) maternal age was 27 (23-31) y; 46.2% of the pregnant women had pregestational body mass index >= 25 kg/m(2), 18.1% had gestational diabetes mellitus, and 11.2% had hypertension. Regarding the newborns, 68 (9.3%) were classified as small for gestational age, 545 (74.2%) as appropriate size for gestational age, and 121 (16.5%) as large for gestational age. In adjusted logistic regression models, a lower chance of being large for gestational age was observed among the children of women classified in the third tertile (versus the first tertile) for intake of polyunsaturated fatty acids (odds ratio {[}OR], 0.52; 95% confidence interval {[}CI], 0.31-0.89; P = 0.02), omega-3 fatty acids (OR, 0.48; 95% CI, 0.28-0.80; P = 0.005), and omega-6 fatty acids (OR, 0.56; 95% CI, 0.33-0.96; P = 0.04) and for ratios of polyunsaturated to saturated fatty acids (OR, 0.54; 95% CI, 0.32-0.92; P = 0.03) and hypocholesterolemic to hypercholesterolemic fatty acids (OR, 0.51; 95% CI, 0.30-0.87; P = 0.01). Conclusions: The data suggest that better-quality fat in the maternal diet can reduce the chance of a large-forgestational-age newborn. (C) 2021 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 18/06746-8 - Quality of diet during pregnancy and its relationship with birth weight
Grantee:Izabela da Silva Santos
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 17/18980-2 - Adherence to the goals of a lifestyle intervention among overweight pregnant women and its effect on perinatal outcomes
Grantee:Lívia Castro Crivellenti
Support Opportunities: Scholarships in Brazil - Post-Doctoral