Comparison Between Nylon and Polyglactin Sutures i... - BV FAPESP
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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Comparison Between Nylon and Polyglactin Sutures in Pediatric Cataract Surgery: A Randomized Controlled Clinical Trial

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Author(s):
Melega, V, Mathias ; dos Reis, Roberto [1] ; Cavalcanti Lira, Rodrigo Pessoa [2] ; de Oliveira, Denise Fornazari [1] ; Leite Arieta, Carlos Eduardo [1] ; Alves, Monica [1]
Total Authors: 6
Affiliation:
[1] Melega, Mathias, V, Univ Estadual Campinas, Sch Med Sci, Sao Paulo - Brazil
[2] Fed Univ Pernambuco UFPE, Sch Med Sci, Recife, PE - Brazil
Total Affiliations: 2
Document type: Journal article
Source: FRONTIERS IN MEDICINE; v. 8, AUG 27 2021.
Web of Science Citations: 0
Abstract

Purpose: To compare the performance of nylon sutures to that of polyglactin sutures in pediatric patients undergoing cataract surgery.</p> \& nbsp;</p> Setting: University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil</p> \& nbsp;</p> Design: A prospective, randomized, partially masked, single-site clinical trial. ().</p> \& nbsp;</p> Methods: A total of 80 eyes from 80 patients who underwent pediatric cataract surgery were randomized into two groups in block sizes of four. Group A consisted of 41 patients whose surgical incisions were sutured with polyglactin 10-0 material. Group B consisted of 39 patients whose surgical incisions were sutured with nylon 10-0 material. The primary outcome was frequency of suture-related complications in each group. Secondary outcomes were the frequency with which suture removal was necessary.</p> \& nbsp;</p> Results: The incidence of suture-related complications within 6 months of follow up was 0 out of 41 eyes (0.00%) in the polyglactin group and 17 out of 39 eyes (43.59%) in the nylon control group (p < 0.001). In all of the eyes with suture-related complications, the sutures were promptly removed. The most frequent complications were vascularization near the suture (17.95%) and loose sutures (17.95%). No ocular or systemic study-related adverse events were observed.</p> \& nbsp;</p> Conclusions: Polyglactin sutures were found to be safe and effective for pediatric patients undergoing cataract surgery. Their lower rate of complications and reduced likelihood of removal (and the subsequent need for general anesthesia) make their use preferrable to that of nylon sutures. This study represents the first controlled randomized clinical trial to compare nylon sutures to polyglactin sutures in pediatric patients undergoing cataract surgery.</p> \& nbsp;</p> (AU)

FAPESP's process: 14/19138-5 - Ocular tissue biobank implementation and investigation of new pathophysiological mechanisms of anterior segment eye diseases
Grantee:Mônica de Cássia Alves
Support Opportunities: Research Grants - Young Investigators Grants