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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Otoacoustic emissions in neonates exposed to smoke during pregnancy

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Durante, Alessandra Spada [1] ; do Nascimento, Cristina Moraes [1] ; Lopes, Cristiane [1]
Total Authors: 3
[1] Santa Casa Sao Paulo, Escola Ciencias Med, Sao Paulo, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Brazilian Journal of Otorhinolaryngology; v. 87, n. 2, p. 193-199, MAR-APR 2021.
Web of Science Citations: 0

Introduction: The toxic substances present in cigarette smoke can damage cochlea hair cells. This effect has been investigated by measuring otoacoustic emissions. Objective: To investigate the impact of stimuli on otoacoustic emissions, comparing neonates with and without exposure to cigarette smoke during pregnancy. Methods: Transient-evoked otoacoustic emissions, evoked by a click stimulus, and distortion product otoacoustic emissions, evoked by two tones tests were conducted in both ears, using an Interacoustic TITAN device. The study included 105 neonates divided into two groups: a study group, comprising 47 neonates exposed to smoke during pregnancy; and a control group comprized of 58 neonates who were not exposed. All participants had normal neonatal hearing screening. Results: No statistical differences in distortion product otoacoustic emissions response levels were found between the groups. In the transient-evoked otoacoustic emissions tests lower response levels were observed in the study group than the control group in frequency band analysis of the right ear, with statistically significant differences in signals and signal-noise ratio (except at 1 kHz). Conclusion: The impact of smoking exposure could be analyzed through transient-evoked otoacoustic emissions in neonates. The group effect of smoke exposure during pregnancy was evidenced by a reduction in transient-evoked otoacoustic emissions levels. This same effect was not observed for the analyses performed on distortion product otoacoustic emissions levels. (C) 2019 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda. (AU)

FAPESP's process: 14/15810-0 - Correlation of wideband tympanometry with the audiological results in neonates exposed to passive smoke
Grantee:Alessandra Spada Durante
Support Opportunities: Regular Research Grants