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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Techno-economical optimization of uvaia (Eugenia pyriformis) extraction using supercritical fluid technology

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Klein, Elissandro Jair [1] ; Nunes Carvalho, Pedro Ivo [2] ; Nathia-Neves, Grazielle [2] ; Vardanega, Renata [2, 3] ; Meireles, M. Angela A. [2] ; da Silva, Edson Antonio [4] ; Adeodato Vieira, Melissa Gurgel [1]
Total Authors: 7
[1] Univ Estadual Campinas, Sch Chem Engn, UNICAMP, Albert Einstein Ave 500, BR-13083852 Campinas, SP - Brazil
[2] Univ Estadual Campinas, Sch Food Engn, LASEFI Dept Food Engn, UNICAMP, Monteiro Lobato St 80, BR-13083862 Campinas, SP - Brazil
[3] Entourage Phytolab, Tabapua St 111, BR-04533010 Sao Paulo, SP - Brazil
[4] Western Parana State Univ, Ctr Engn & Exact Sci, Fac St 645, BR-85903000 Toledo, Parana - Brazil
Total Affiliations: 4
Document type: Journal article
Web of Science Citations: 0

This work presents an economic evaluation of supercritical fluid extraction (SFE) process from uvaia leaves. Extractions were performed at a previously optimized condition of pressure (200 bar) and temperature (60 degrees C) and were evaluated with the addition of 5% of two different co-solvents (ethyl acetate and ethanol). A scale-up study was performed by adopting constant values for the solvent to feed mass ratio (S/F) and the extraction time as criteria. Two different scales were assessed: 5-fold and 10-fold (vessel volume and mass due to the constant bed density). An economic evaluation using SuperPro Designer 8.5 (R) to estimate the cost of manufacturing (COM) by testing 3 different scenarios was also performed. The addition of co-solvents resulted in lower estimated production costs, and the addition of 5% (w/w) of ethanol showed the best results among the conditions evaluated. The COM values are in a range from 622.9 to 1102.6 US\$/kg extract. (AU)

FAPESP's process: 19/07596-2 - Bioactivity-profiling of crude extracts of Eugenia pyriformis using 1H NMR metabolomics and quadruple high-resolution alpha-amylase/alpha-glucosidase/PTP1B/radical scavenging profiling combined with HPLC-PDA-HRMS-SPE-NMR
Grantee:Elissandro Jair Klein
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 15/22952-9 - Obtaining and purification of ± and ß-amyrin from leaves Uvaia (Eugenia pyriformis Cambess)
Grantee:Elissandro Jair Klein
Support type: Scholarships in Brazil - Doctorate