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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Mid- to Long-Term Magnetic Resonance Imaging Results of Two Prolapse Surgeries for Apical Defect: A Secondary Analysis of a Randomized Controlled Trial

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Santos Juniors, Luiz Carlos [1] ; Oliveira Brito, Luiz Gustavo [1] ; de Castro, Edilson Benedito [1] ; Dertkigil, Sergio [1] ; Teatin Juliato, Cassia Raquel [1]
Total Authors: 5
[1] Univ Estadual Campinas, Fac Ciencias Med, Dept Obstet & Gynecol, Pelv Floor Dysfunct Div, Campinas, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Revista Brasileira de Ginecologia e Obstetrícia; v. 43, n. 1, p. 46-53, JAN 2021.
Web of Science Citations: 0

Objective: Magnetic resonance imaging (MRI) has been considered another tool for use during the pre- and postoperative periods of the management of pelvic-organ prolapse (POP). However, there is little consensus regarding its practical use for POP and the association between MRI lines of reference and physical examination. We aimed to evaluate the mid- to long-term results of two surgical techniques for apical prolapse. Methods: In total, 40 women with apical POP randomized from 2014 to 2016 underwent abdominal sacrocolpopexy (ASC group; n = 20) or bilateral vaginal sacrospinous fixation with an anterior mesh (VSF-AM group; n = 20). A physical examination using the POP Quantification System (POP-Q) for staging (objective cure) and the International Consultation on Incontinence Questionnaire-Vaginal Symptoms (ICIQ-VS: subjective cure), were applied and analyzed before and one year after surgery respectively. All MRI variables (pubococcigeous line {[}PCL], bladder base {[}BB], anorectal junction {[}ARJ], and the estimated levator ani subtended volume {[}eLASV]) were investigated one year after surgery. Significance was established at p < 0.05. Results: After a mean 27-month follow-up, according to the MRI criteria, 60% of the women were cured in the VSF-AM group versus 45% in ASC group (p = 0.52). The POP-Q and objective cure rates by MRI were correlated in the anterior vaginal wall (p = 0.007), but no correlation was found with the subjective cure. The eLASV was larger among the patients with surgical failure, and a cutoff of = 33.5 mm3 was associated with postoperative failure (area under the receiver operating characteristic curve {[}ROC]: 0.813; p = 0.002). Conclusion: Both surgeries for prolapse were similar regarding the objective variables (POP-Q measurements and MRI cure rates). Larger eLASV areas were associated with surgical failure. (AU)

FAPESP's process: 16/24065-2 - Final vaginal axis in patients submitted to surgical prolapse correction - a randomized controlled trial
Grantee:Cássia Raquel Teatin Juliato
Support type: Regular Research Grants