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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Role of Anaphase-Promoting Complex/Cyclosome (APC/C) in Plant Reproduction

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Saleme, Marina de Lyra Soriano [1] ; Andrade, Ingrid Rocha [1] ; Eloy, Nubia Barbosa [1]
Total Authors: 3
[1] Univ Sao Paulo, Dept Biol Sci, Escola Super Agr Luiz de Queiroz, Piracicaba - Brazil
Total Affiliations: 1
Document type: Review article
Source: FRONTIERS IN PLANT SCIENCE; v. 12, FEB 24 2021.
Web of Science Citations: 3

Most eukaryotic species propagate through sexual reproduction that requires male and female gametes. In flowering plants, it starts through a single round of DNA replication (S phase) and two consecutive chromosome segregation (meiosis I and II). Subsequently, haploid mitotic divisions occur, which results in a male gametophyte (pollen grain) and a female gametophyte (embryo sac) formation. In order to obtain viable gametophytes, accurate chromosome segregation is crucial to ensure ploidy stability. A precise gametogenesis progression is tightly regulated in plants and is controlled by multiple mechanisms to guarantee a correct evolution through meiotic cell division and sexual differentiation. In the past years, research in the field has shown an important role of the conserved E3-ubiquitin ligase complex, Anaphase-Promoting Complex/Cyclosome (APC/C), in this process. The APC/C is a multi-subunit complex that targets proteins for degradation via proteasome 26S. The functional characterization of APC/C subunits in Arabidopsis, which is one of the main E3 ubiquitin ligase that controls cell cycle, has revealed that all subunits investigated so far are essential for gametophytic development and/or embryogenesis. (AU)

FAPESP's process: 17/10333-8 - APC as an entry point to study small molecule regulation of the cell cycle
Grantee:Nubia Barbosa Eloy
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 20/00888-5 - APC as an entry point to study small molecule regulation of the cell cycle
Grantee:Marina de Lyra Soriano Saleme
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 20/02353-1 - Use of anaphase promoter complex genes to increase biomass
Grantee:Ingrid Andrade Rocha
Support type: Scholarships in Brazil - Master