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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Oral candidiasis prevalence in human immunodeficiency virus-1 and pulmonary tuberculosis coinfection: A systematic review and meta-analysis

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Ramos Pena, Diana Estefania [1] ; Alencar Ramos Innocentini, Lara Maria [2, 3] ; Pereira Saraiva, Maria Conceicao [4] ; Lourenco, Alan Grupioni [5] ; Fragoso Motta, Ana Carolina [2]
Total Authors: 5
[1] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Oral & Maxillofacial Surg & Periodontol, Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Stomatol Publ Hlth & Forens Dent, Ribeirao Preto, SP - Brazil
[3] Univ Sao Paulo, Ribeirao Preto Med Sch, Div Dent & Stomatol, Clin Hosp, Ribeirao Preto, SP - Brazil
[4] Univ Sao Paulo, Dept Pediat Dent, Sch Dent Ribeirao Preto, Ribeirao Preto, SP - Brazil
[5] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Basic & Oral Biol, Ribeirao Preto, SP - Brazil
Total Affiliations: 5
Document type: Review article
Source: Microbial Pathogenesis; v. 150, JAN 2021.
Web of Science Citations: 0

Background: Human immunodeficiency virus-1 (HIV-1) infected people are more likely to develop tuberculosis (TB), being the leading cause of death in HIV-1. Candida spp has emerged as potential pathogenic fungi in patients with HIV and bronchopulmonary diseases. This systematic review summarizes the available data on the occurrence of oral candidiasis (OC) in the HIV-1/pulmonary tuberculosis (pTB) coinfection. Methods: Articles that reported the occurrence of OC in the HIV-1-pTB coinfection were searched in eight databases. Observational studies that evaluated the association between OC and HIV-1-pTB coinfection were selected. The risk of bias was assessed using the meta-analysis of statistics assessment and review instrument (MAStARI) checklist. Results: From a total of 1858 records, after application of inclusion and exclusion criteria, six were included in the meta-analysis. Three studies were at low risk, one at moderate risk, and two at high risk of bias. Considerable heterogeneity across the studies was identified. Meta-analyses performed showed no difference in the prevalence of OC between HIV-1 patients with and without pTB coinfection (odds ratio M-H = 1.77; 95% CI = 0.69 to 4.52). Conclusion: There is no association between OC and HIV-1/pTB coinfection. (AU)

FAPESP's process: 16/22476-5 - Influence of periodontal treatment on the levels of oral inflammatory markers in HIV-infected patients
Grantee:Vanessa de Oliveira Teles
Support Opportunities: Scholarships in Brazil - Scientific Initiation