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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

BKC-2, a New BKC Variant Detected in MCR-9.1-Producing Enterobacter hormaechei subsp. xiangfangensis

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Author(s):
Martins, Willames M. B. S. [1, 2] ; Martins, Evelin R. [3] ; de Andrade, Leticia K. [3] ; Farzana, Refath [1] ; Walsh, Timothy R. [4] ; Toleman, Mark A. [1] ; Nogueira, Mara C. L. [3] ; Gales, Ana C. [2]
Total Authors: 8
Affiliation:
[1] Cardiff Univ, Div Infect & Immun, Dept Med Microbiol, Cardiff - Wales
[2] Univ Fed Sao Paulo UNIFESP, Escola Paulista Med, Dept Internal Med, Div Infect Dis, Sao Paulo - Brazil
[3] Fac Med Sao Jose do Rio Preto FAMERP, Ctr Invest Microrganismos, Sao Jose Do Rio Preto, SP - Brazil
[4] Univ Oxford, Dept Zool, Oxford - England
Total Affiliations: 4
Document type: Journal article
Source: Antimicrobial Agents and Chemotherapy; v. 65, n. 3 MAR 2021.
Web of Science Citations: 0
Abstract

We characterized a multidrug-resistant (MDR) Enterobacter spp. isolate highlighting the genetic aspects of the antimicrobial resistance genes. An Enterobacter spp. isolate (Ec61) was recovered in 2014 from a transtracheal aspirate sample from a patient admitted to a Brazilian tertiary hospital and submitted to further microbiological and genomic characterization. Ec61 was identified as Enterobacter hormaechei subsp. xiangfangensis strain ST451, showing an MDR profile and the presence of genes codifying the new beta-lactamase variants BKC-2 and ACT-84 and the mobile colistin resistance gene mcr-9.1. (AU)

FAPESP's process: 18/24431-4 - Investigation and characterization of bacteriophages with lytic activity against the main epidemic bacterial clones recovered from Brazilian hospitals
Grantee:Willames Marcos Brasileiro da Silva Martins
Support Opportunities: Scholarships in Brazil - Post-Doctoral