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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Trends in Melanoma Mortality in Brazil: A Registry-Based Study

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Marta, Guilherme Nader [1, 2] ; Munhoz, Rodrigo Ramella [1, 3] ; Teixeira, Monica La Porte [4] ; Waldvogel, Bernadette Cunha [4] ; de Camargo, Veridiana Pires [1, 2] ; Feher, Olavo [1, 3] ; Sanches, Jose Antonio [5]
Total Authors: 7
[1] Fac Med Univ Sao Paulo, Inst Canc Estado Sao Paulo, Med Oncol Serv, Sao Paulo - Brazil
[2] Oncol DOr, Rio De Janeiro - Brazil
[3] Hosp Sirio Libanes, Med Oncol Serv, Sao Paulo - Brazil
[4] Fundacao SEADE, Sao Paulo - Brazil
[5] Univ Sao Paulo, Dermatol Dept, Fac Med, Sao Paulo - Brazil
Total Affiliations: 5
Document type: Journal article
Source: JCO GLOBAL ONCOLOGY; v. 6, p. 1766-1771, NOV 2020.
Web of Science Citations: 0

PURPOSE A substantial increase in melanoma incidence has been consistently observed worldwide over the past decades. However, melanoma mortality rates have remained stable or declined over the past years in most regions. Given the paucity of melanoma mortality data for different Brazilian regions, we sought to describe melanoma mortality trends in southeastern Brazil and their relationship with demographic variables. MATERIALS AND METHODS A cross-sectional registry-based analysis was conducted to describe melanoma mortality trends in the state of SAo Paulo, Brazil, from 1996 to 2016. Demographic information from melanoma-related death records, including sex and age, was collected from the FundacAo Sistema Estadual de Analise de Dados database. The annual percentage change (APC) was calculated to identify mortality trends over the period. RESULTS An increasing melanoma mortality trend was detected among males, regardless of age (APC, 1.72%; P < .001), and was more pronounced for men >= 60 years old (APC, 2.63%; P < .001). Melanoma mortality rates have also increased for patients >= 60 years old, regardless of sex (APC, 1.11%; P < .001). A non-statistically significant increase in the overall melanoma mortality rate was observed over the 20-year period analyzed (APC, 0.36%; P = .4). CONCLUSION Our data suggest a stable melanoma mortality over the past two decades for the overall population studied; however, a significant increase in melanoma mortality rates has been demonstrated among males and in the population >= 60 years old, emphasizing the need to implement prevention strategies and expand access to effective therapies for this population. (c) 2020 by American Society of Clinical Oncology (AU)

FAPESP's process: 12/02121-7 - Historical recovery of skin cancer mortality from 1970 to 2010 in the State of São Paulo, Brazil
Grantee:Guilherme Nader Marta
Support Opportunities: Scholarships in Brazil - Scientific Initiation