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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A novel dispersive liquid-liquid microextraction using a low density deep eutectic solvent-gas chromatography tandem mass spectrometry for the determination of polycyclic aromatic hydrocarbons in soft drinks

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Caldeirao, Lucas [1, 2] ; Fernandes, Jose O. [2] ; Gonzalez, Mario Henrique [3] ; Godoy, Helena Teixeira [1] ; Cunha, Sara C. [2]
Total Authors: 5
[1] Univ Campinas UNICAMP, Fac Food Engn, BR-13083862 Campinas, SP - Brazil
[2] Univ Porto, Lab Bromatol & Hydrol, LAQV REQUIMTE, Fac Pharm, Porto - Portugal
[3] Sao Paulo State Univ UNESP, Natl Inst Alternat Technol Detect Toxicol Evaluat, Dept Chem & Environm Sci, BR-15054000 Sao Josedo Do Rio Preto, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Journal of Chromatography A; v. 1635, JAN 4 2021.
Web of Science Citations: 1

Ready-to-drink teas can provide, if properly packaged, the taste and wellness character of traditional teas. Nevertheless, in tea processing, there may be several contaminations, among which polycyclic aromatic hydrocarbons (PAHs), anthropogenic contaminants that can present carcinogenic and mutagenic properties. In this work, a novel low-density deep eutectic solvent-based dispersive liquid-liquid microextraction (LDDES-DLLME) procedure followed by gas chromatography tandem mass spectrometry (GC-MS/MS) was optimized for analysis of 15 polycyclic aromatic hydrocarbons (PAHs) in ready-to-drink herbal-based beverages. The new deep eutectic solvent (DES) was synthesized with natural compounds (camphor and hexanoic acid). Several parameters of the extraction procedure such as type and volume of extraction solvent, type, volume of dispersive solvent, and time of extraction were evaluated to achieve the highest yield and to attain the lowest detection limits. The validated method showed very low limits of detection (0.01 mu g L-1) and quantification (0.2 mu g L-1), good interand intra-day precisions (RSD < 16.87%), and recoveries higher than 69%. The method was applied to 16 type of samples and it was found total PAHs levels ranging from 0.20 to 1.82 mu g L-1. The developed LDDES-DLLME showed a reliable and innovative alternative for the extraction of PAHs from beverages, cost-effective and environmentally friendly, and providing a satisfactory throughput. (C) 2020 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 17/18531-3 - Green analytical chemistry: from sample preparation to trace element determinations by inductively coupled plasma mass spectrometry (ICP-MS)
Grantee:Mario Henrique Gonzalez
Support type: Regular Research Grants
FAPESP's process: 19/22113-8 - Natural Deep Eutectic Solvents: synthesis, characterization, and application for the determination of As, Cd, Cr, Hg, Se, and V in environmental samples using ICP-MS
Grantee:Mario Henrique Gonzalez
Support type: Regular Research Grants
FAPESP's process: 17/05048-2 - Plants tadiotionally used for infusion: Sample preparation techniques and determination of contaminants.
Grantee:Lucas Caldeirão Rodrigues Miranda
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 18/25746-9 - Deep eutectic solvents in sample preparation method for determination of contaminants in ready-to-drink teas.
Grantee:Lucas Caldeirão Rodrigues Miranda
Support type: Scholarships abroad - Research Internship - Doctorate