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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Polyphenol oxidase-based electrochemical biosensors: A review

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Author(s):
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Raymundo-Pereira, Paulo A. [1] ; Silva, Tiago A. [2] ; Caetano, Fabio R. [3] ; Ribovski, Lais [1] ; Zapp, Eduardo [4] ; Brondani, Daniela [4] ; Bergamini, Marcio F. [3] ; Marcolino, Jr., Luiz H. [3] ; Banks, Craig E. [5] ; Oliveira, Jr., Osvaldo N. [1] ; Janegitz, Bruno C. [6] ; Fatibello-Filho, Orlando [7]
Total Authors: 12
Affiliation:
[1] Univ Sao Paulo, Sao Carlos Inst Phys, Sao Carlos, SP - Brazil
[2] Ctr Fed Educ Tecnol Minas Gerais CEFET MG, Dept Met & Quim, BR-35180008 Timoteo, MG - Brazil
[3] Univ Fed Parana UFPR, Dept Quim, Lab Sensores Eletroquim LabSensE, BR-81531980 Curitiba, PR - Brazil
[4] Univ Fed Santa Catarina, Dept Exact Sci & Educ, BR-89036256 Florianopolis, SC - Brazil
[5] Manchester Metropolitan Univ, Fac Sci & Engn, Chester St, Manchester M1 5GD, Lancs - England
[6] Univ Fed Sao Carlos, Dept Nat Sci Math & Educ, BR-13600970 Araras, SP - Brazil
[7] Univ Fed Sao Carlos, Dept Chem, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 7
Document type: Review article
Source: Analytica Chimica Acta; v. 1139, p. 198-221, DEC 1 2020.
Web of Science Citations: 6
Abstract

The detection of phenolic compounds is relevant not only for their possible benefits to human health but also for their role as chemical pollutants, including as endocrine disruptors. The required monitoring of such compounds on-site or in field analysis can be performed with electrochemical biosensors made with polyphenol oxidases (PPO). In this review, we describe biosensors containing the oxidases tyrosinase and laccase, in addition to crude extracts and tissues from plants as enzyme sources. From the survey in the literature, we found that significant advances to obtain sensitive, robust biosensors arise from the synergy reached with a diversity of nanomaterials employed in the matrix. These nanomaterials are mostly metallic nanoparticles and carbon nanostructures, which offer a suitable environment to preserve the activity of the enzymes and enhance electron transport. Besides presenting a summary of contributions to electrochemical biosensors containing PPOs in the last five years, we discuss the trends and challenges to take these biosensors to the market, especially for biomedical applications. (C) 2020 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 20/01050-5 - Development and application of electrochemical and photoelectrochemical sensors for the determination of emerging contaminants in environmental samples
Grantee:Orlando Fatibello Filho
Support type: Regular Research Grants
FAPESP's process: 18/22214-6 - Toward a convergence of technologies: from sensing and biosensing to information visualization and machine learning for data analysis in clinical diagnosis
Grantee:Osvaldo Novais de Oliveira Junior
Support type: Research Projects - Thematic Grants
FAPESP's process: 17/21898-6 - New conductive devices for application in electrochemical sensing and biosensing
Grantee:Bruno Campos Janegitz
Support type: Regular Research Grants
FAPESP's process: 17/21097-3 - Bee-agriculture interactions: perspectives to sustainable use
Grantee:Osmar Malaspina
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 16/01919-6 - Design and fabrication of nanostructured flexible devices for biomarkers detection
Grantee:Paulo Augusto Raymundo Pereira
Support type: Scholarships in Brazil - Post-Doctorate