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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses

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Author(s):
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Alonso, Juliana de Moura [1] ; Esper, Carolina Soares [1] ; Figueiredo Pantoja, Jose Carlos [2] ; Rosa, Gustavo dos Santos [1] ; Giampietro, Rodrigo Rosa [3] ; dos Santos, Bruna [4] ; Guerra, Simony Trevizan [2] ; Ribeiro, Marcio Garcia [2] ; Takahira, Regina Kiomi [4] ; Watanabe, Marcos Jun [1] ; Garcia Alves, Ana Liz [1] ; Rodrigues, Celso Antonio [1] ; Mogollon Garcia, Henry David [1] ; Hussni, Carlos Alberto [1]
Total Authors: 14
Affiliation:
[1] Univ Estadual Paulista Unesp, Sch Vet Med & Anim Sci, Dept Vet Surg & Anim Reprod, Botucatu, SP - Brazil
[2] Univ Estadual Paulista Unesp, Sch Vet Med & Anim Sci, Dept Anim Prod & Prevent Vet Med, Botucatu, SP - Brazil
[3] Univ Estadual Paulista UNESP, Botucatu Med Sch, Dept Internal Med, Botucatu, SP - Brazil
[4] Univ Estadual Paulista Unesp, Sch Vet Med & Anim Sci, Dept Vet Clin, Botucatu, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Research in Veterinary Science; v. 132, p. 237-242, OCT 2020.
Web of Science Citations: 2
Abstract

Difference in blood and peritoneal glucose (DBPG) is used in clinical practice to support a diagnosis of septic peritonitis in horses. It is inexpensive, easy and rapid to perform. The aim of this study was to evaluate the accuracy of the DBPG to differentiate between septic and non-septic peritonitis in horses. Blood and peritoneal fluids were harvested from suspected animals. Plasma and peritoneal glucose levels, total nucleated cell count, direct microscopic and microbiological examinations of the peritoneal fluid were evaluated. Using DBPG levels, the animals were classified into two groups: difference >= 50 mg/dL (positive test) and difference < 50 mg/dL (negative test). Positive microbiological examination and/or presence of bacteria in direct microscopic examination was used as a gold standard to detect septic peritonitis. The accuracy parameters analysed were: sensitivity, specificity, and positive/negative predictive values, for which the results were respectively: 0.23, 0.91, 0.60 and 0.67. Due to poor accuracy, other cut-off margins and peritoneal glucose concentrations were evaluated. The test was considered most accurate when the DBPG was zero with sensitivity, specificity, and positive/negative predictive values of 0.85, 0.82, 0.73, 0.90 respectively. Peritoneal glucose concentrations alone were not a reliable feature to detect peritonitis. DBPG >= 50 mg/dL, widely used for the diagnosis of septic peritonitis, does not have a good accuracy and the DBPG = 0 has a better accuracy for detecting the disease. (AU)

FAPESP's process: 18/16013-8 - Accuracy of blood and peritoneal glucose difference for septic peritonitis identification in horses
Grantee:Carolina Soares Esper
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 16/08712-8 - INTRAPERITONEAL CEFTRIAXONE IN EQUINE PERITONITIS TREATMENT
Grantee:Juliana de Moura Alonso
Support type: Scholarships in Brazil - Post-Doctorate