Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of perioperative hyperglycemia on surgical site infection in abdominal surgery: A prospective cohort study

Full text
Bellusse, Gislaine Cristhina [1] ; Ribeiro, Julio Cesar [1] ; Martins de Freitas, Isabel Cristina [2] ; Galvao, Cristina Maria [3]
Total Authors: 4
[1] Univ Franca, Franca, SP - Brazil
[2] Univ Sao Paulo, Ribeirao Preto Coll Nursing, Epidemiol Ctr, Ribeirao Preto, SP - Brazil
[3] Univ Sao Paulo, Ribeirao Preto Coll Nursing, Ave Bandeirantes 3900, Campus Univ Monte Alegre, BR-14040902 Ribeirao Preto, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: AMERICAN JOURNAL OF INFECTION CONTROL; v. 48, n. 7, p. 781-785, JUL 2020.
Web of Science Citations: 0

Background: Surgical site infection (SSI) remains one of the most frequent complications in abdominal surgery, and hyperglycemia prevention is recommended as a measure to reduce this type of infection. The aims of this study were to estimate the incidence of SSI and to identify the effect of perioperative hyperglycemia on the incidence of this type of infection in patients undergoing abdominal surgery. Methods: We enrolled 484 abdominal surgery patients >= 18 years of age, recruited between July 2016 and May 2017. Data were collected through structured interviews and patient assessments in the perioperative period and at the surgical outpatient clinic (30th day after surgery). Crude and adjusted models were built to identify the effect of hyperglycemia on SSI. Results: The incidence rate of SSI was 20.25%. The attributable fraction for patients exposed to hyperglycemia was 60%. In the multivariable analysis, patients with hyperglycemia, at the end of the surgery and 12 hours later, were more likely to develop this type of infection (relative risk = 1.89 and 2.17, respectively). Conclusions: Perioperative hyperglycemia was identi fied as an independent risk factor for SSI. The evidence generated reinforces the importance of proper glycemic control management in the perioperative period for the prevention of SSI. (C) 2019 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 15/24274-8 - Hypothermia and hyperglycemia effect on the incidence of surgical site infection in gastrointestinal surgery: a cohort study
Grantee:Cristina Maria Galvão
Support Opportunities: Regular Research Grants