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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Ultrahigh hardness and biocompatibility of high-entropy alloy TiAlFeCoNi processed by high-pressure torsion

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Edalati, Parisa [1] ; Floriano, Ricardo [2] ; Tang, Yongpeng [1] ; Mohammadi, Abbas [1] ; Pereira, Karina Danielle [2, 3] ; Luchessi, Augusto Ducati [2, 3] ; Edalati, Kaveh [1]
Total Authors: 7
[1] Kyushu Univ, Int Inst Carbon Neutral Energy Res WPI I2CNER, WPI, Fukuoka - Japan
[2] Univ Campinas UNICAMP, Sch Appl Sci, Limeira, SP - Brazil
[3] Sao Paulo State Univ UNESP, Inst Biosci, Rio Claro, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Materials Science & Engineering C-Materials for Biological Applications; v. 112, JUL 2020.
Web of Science Citations: 0

Despite significant studies on mechanical properties of high-entropy alloys (HEAs), there have been limited attempts to examine the biocompatibility of these alloys. In this study, a lattice-softened high-entropy alloy TiAlFeCoNi with ultrahigh hardness (examined by Vickers method), low elastic modulus (examined by nanoindentation) and superior activity for cell proliferation/viability/cytotoxicity (examined by MTT assay) was developed by employing imperial data and thermodynamic calculations. The designated alloy after casting was processed further by high-pressure torsion (HPT) to improve its hardness via the introduction of nanograins, dislocations and order-disorder transformation. The TiAlFeCoNi alloy with the L2(1)-BCC crystal structure exhibited 170-580% higher hardness and 260-1020% better cellular metabolic activity compared to titanium and Ti-6Al-7Nb biomaterials, suggesting the high potential of HEAs for future biomedical applications. (AU)

FAPESP's process: 18/15968-4 - Synthesis and Characterization of High Entropy Alloys based on TiFe System
Grantee:Ricardo Floriano
Support Opportunities: Regular Research Grants
FAPESP's process: 13/23620-4 - Functional characterization of the translation factor EIF5A isoform A
Grantee:Karina Danielle Pereira
Support Opportunities: Scholarships in Brazil - Doctorate