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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Comparison between Plasma Electrolytic Oxidation Coating and Sandblasted Acid-Etched Surface Treatment: Histometric, Tomographic, and Expression Levels of Osteoclastogenic Factors in Osteoporotic Rats

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Correia Momesso, Gustavo Antonio [1] ; de Souza Santos, Anderson Maikon [1] ; Fonseca e Santos, Joao Matheus [1] ; da Cruz, Nilson Cristino [2] ; Okamoto, Roberta [3] ; Ricardo Barao, Valentim Adelino [4] ; Siroma, Rafael Shinoske [5] ; Shibli, Jamil Awad [5] ; Faverani, Leonardo Perez [1]
Total Authors: 9
[1] Sao Paulo State Univ Unesp, Aracatuba Sch Dent, Dept Diag & Surgery, Sao Paulo 16015050 - Brazil
[2] Sao Paulo State Univ Unesp, Technol Plasma Lab LaPTec, Expt Campus Sorocaba, Sorocaba 18087180 - Brazil
[3] Sao Paulo State Univ Unesp, Aracatuba Sch Dent, Dept Basic Sci, Sao Paulo 16018800 - Brazil
[4] Univ Campinas Unicamp, Piracicaba Sch Dent, Dept Prosthodont & Periodontol, Sao Paulo 13414903 - Brazil
[5] Univ Guarulhos UnG, Dept Periodontol & Oral Implantol, Dent Res Div, Guarulhos 07115230, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: MATERIALS; v. 13, n. 7 APR 2020.
Web of Science Citations: 0

Plasma electrolytic oxidation (PEO) has been a promising surface coating with better mechanical and antimicrobial parameters comparing to conventional treatment surfaces. This study evaluated the peri-implant bone repair using (PEO) surface coatings compared with sandblasted acid (SLA) treatment. For this purpose, 44 Wistar rats were ovariectomized (OVX-22 animals) or underwent simulated surgery (SS-22 animals) and received implants in the tibia with each of the surface coatings. The peri-implant bone subsequently underwent molecular, microstructural, bone turnover, and histometric analysis. Real-time PCR showed a higher expression of osteoprotegerin (OPG), receptor activator of nuclear kappa-B ligand (RANKL), and osteocalcin (OC) proteins in the SLA/OVX and PEO/SS groups (p < 0.05). Computed microtomography, confocal microscopy, and histometry showed similarity between the PEO and SLA surfaces, with a trend toward the superiority of PEO in OVX animals. Thus, PEO surfaces were shown to be promising for enhancing peri-implant bone repair in ovariectomized rats. (AU)

FAPESP's process: 16/20297-6 - The influence of commercially pure Titanium (cpTi) coating with Ca and P incorporation produced by plasma electrolytic oxidation on low density bone: An in vitro, ex-vivo and in vivo study
Grantee:Leonardo Perez Faverani
Support type: Regular Research Grants