| Full text | |
| Author(s): Show less - |
Cunha, Mariana Sequetin
[1]
;
Faria, Nuno Rodrigues
[2]
;
Caleiro, Giovana Santos
[1, 3]
;
Candido, Darlan Silva
[2]
;
Hill, Sarah C.
[2]
;
Claro, Ingra Morales
[3]
;
da Costa, Antonio Charlys
[3]
;
Nogueira, Juliana Silva
[1]
;
Maeda, Adriana Yurika
[1]
;
da Silva, Fernanda Gisele
[1]
;
de Souza, Renato Pereira
[1]
;
Spinola, Roberta
[4]
;
Tubaki, Rosa Maria
[5]
;
Tironi de Menezes, Regiane Maria
[5]
;
Abade, Leandro
[2]
;
Mucci, Luis Filipe
[6]
;
Sampaio Tavares Timenetsky, Maria do Carmo
[1]
;
Sabino, Esther
[3]
Total Authors: 18
|
| Affiliation: | [1] Adolfo Lutz Inst, Sao Paulo, SP - Brazil
[2] Univ Oxford, Dept Zool, Oxford - England
[3] Univ Sao Paulo, Inst Trop Med, Sao Paulo, SP - Brazil
[4] Ctr Vigilancia Epidemiol Prof Alexandre Vranjac, Sao Paulo, SP - Brazil
[5] Superintendence Control Endem Dis, Sao Paulo, SP - Brazil
[6] Superintendence Control Endem Dis, Taubate, SP - Brazil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | Acta Tropica; v. 205, MAY 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
The southeastern region of Brazil has recently experienced the largest yellow fever disease outbreak in decades. Since July 2016 epizootic events were reported in Sao Paulo state's north region, where 787 Culicidae were captured as part of public health surveillance efforts and tested using real-time quantitative PCR. One Aedes scapularis pool collected in November 2016 in an agriculture area in Urupes city tested positive for YFV-RNA. Using a validated multiplex PCR approach we were able to recover a complete virus genome sequence from this pool. Phylogenetic analysis of the novel strain and publicly available data indicates that the belongs to the South American genotype 1 clade circulating in Sao Paulo state and is basal to the recent outbreak clade in southeast Brazil. Our findings highlight the need of additional studies, including vector competence studies, to disentangle the role of Aedes scapularis in yellow fever transmission in the Americas. (AU) | |
| FAPESP's process: | 17/00021-9 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil |
| Grantee: | Antonio Charlys da Costa |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 18/14389-0 - Brazil-UK Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology (CADDE) |
| Grantee: | Ester Cerdeira Sabino |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 16/01735-2 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil |
| Grantee: | Ester Cerdeira Sabino |
| Support Opportunities: | Regular Research Grants |