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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evaluation of the Dot-ELISA as a diagnostic test for human strongyloidiasis based on the detection of IgA in saliva

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Author(s):
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Bosqui, Larissa Rodrigues [1] ; Corral, Marcelo Andreetta [2] ; Levy, Debora [2] ; Bydlowski, Sergio Paulo [2] ; Borges Gryschek, Ronaldo Cesar [2] ; Custodio, Luiz Antonio [1] ; Pavanelli, Wander Rogerio [1] ; Conchon-Costa, Ivete [1] ; Costa-Cruz, Julia Maria [3] ; de Paula, Fabiana Martins [2] ; Costa, Idessania Nazareth [1]
Total Authors: 11
Affiliation:
[1] Univ Estadual Londrina, UEL, Rodovia Celso Garcia Cid Campus Univ, BR-86051990 Londrina, Parana - Brazil
[2] FMUSP, Hosp Clin, Av Dr Arnaldo 455, BR-01246903 Sao Paulo, SP - Brazil
[3] Univ Fed Uberlandia, UFU, Av Amazonas S-N, Bloco 4C, BR-38400902 Uberlandia, MG - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Acta Tropica; v. 203, MAR 2020.
Web of Science Citations: 0
Abstract

This study aimed to evaluate the use of saliva samples in the Dot-ELISA test for immunodiagnosis of human strongyloidiasis. The Dot-ELISA presented similar results to the ELISA test, with 70% and 60% sensitivity and 85% and 90% specificity, respectively, for IgA in the saliva. The Dot-ELISA with alternative saliva samples may be a suitable tool for diagnosing human strongyloidiasis, especially in populations with high levels of exposure to helminth. (AU)

FAPESP's process: 13/03304-0 - Molecular diagnosis by detection of specific DNA in blood samples from rats experimentally infected with Strongyloides venezuelensis
Grantee:Fabiana Martins de Paula
Support Opportunities: Regular Research Grants