Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Biomaterial-based possibilities for managing peri-implantitis

Full text
de Avila, Erica D. [1, 2] ; van Oirschot, Bart A. [1, 3] ; van den Beucken, Jeroen J. J. P. [1]
Total Authors: 3
[1] Radboudumc, Regenerat Biomat, Nijmegen - Netherlands
[2] Sao Paulo State Univ UNESP, Dept Dent Mat & Prosthodont, Sch Dent Araraquara, Araraquara, SP - Brazil
[3] Radboudumc, Dept Implantol & Periodontol, Nijmegen - Netherlands
Total Affiliations: 3
Document type: Review article
Web of Science Citations: 0

Peri-implantitis is an inflammatory disease of hard and soft tissues around osseointegrated implants, followed by a progressive damage of alveolar bone. Oral microorganisms can adhere to all types of surfaces by the production of multiple adhesive factors. Inherent properties of materials will influence not only the number of microorganisms, but also their profile and adhesion force onto the material surface. In this perspective, strategies to reduce the adhesion of pathogenic microorganisms on dental implants and their components should be investigated in modern rehabilitation concepts in implant dentistry. To date, several metallic nanoparticle films have been developed to reduce the growth of pathogenic bacteria. However, the main drawback in these approaches is the potential toxicity and accumulative effect of the metals over time. In view of biological issues and in attempt to prevent and/or treat peri-implantitis, biomaterials as carriers of antimicrobial substances have attracted special attention for application as coatings on dental implant devices. This review will focus on biomaterial-based possibilities to prevent and/or treat peri-implantitis by describing concepts and dental implant components suitable for engagement in preventing and treating this disease. Additionally, we raise important criteria referring to the geometric parameters of dental implants and their components, which can directly affect peri-implant tissue conditions. Finally, we overview currently available biomaterial systems that can be used in the field of oral implantology. (AU)

FAPESP's process: 15/03567-7 - Modification of the physicochemical properties with different coating materials of titanium implant abutment surfaces and evaluation of their effects on the development of a polymicrobial community representative of the oral cavity: an in vitro preliminar
Grantee:Érica Dorigatti de Avila
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 16/19650-3 - Functional layer-by-layer coatings for implant abutment surfaces: investigating the effect of controlled release of antibacterial agents on cytokine signaling and production of inflammatory mediators induced by Porphyromonas gingivalis LPS
Grantee:Érica Dorigatti de Avila
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor