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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Niobium Pentachloride Mediated (Hetero)aromatic Aldehyde Friedel-Crafts Hydroxyalkylation with Arenes: An Efficient Strategy to Synthesize Triarylmethanes

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Rodrigues, Shirley M. M. [1] ; Previdi, Daniel [1] ; Baviera, Giovanni S. [1] ; Matias, Alexandre A. [1] ; Donate, Paulo M. [1]
Total Authors: 5
[1] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040901 Ribeirao Preto - Brazil
Total Affiliations: 1
Document type: Journal article
Source: SYNTHESIS-STUTTGART; v. 51, n. 23, p. 4498-4506, DEC 3 2019.
Web of Science Citations: 0

Niobium pentachloride is an efficient and useful Lewis acid to conduct Friedel-Crafts hydroxyalkylation between arenes and (hetero)aromatic aldehydes, to generate triarylmethanes. This practical methodology offers several advantages, such as short reaction time, mild experimental conditions, and excellent yields. (AU)

FAPESP's process: 18/24680-4 - Synthesis and structural modifications of butyrolactone derivatives to obtain new compounds of biological interest
Grantee:Paulo Marcos Donate
Support Opportunities: Regular Research Grants
FAPESP's process: 16/04896-7 - Multicomponent processes to synthesize new compounds of pharmacological interest - Part 2
Grantee:Paulo Marcos Donate
Support Opportunities: Regular Research Grants