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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The first survey of human T-cell lymphotropic viruses (HTLV) in HIV/AIDS patients in Santa Catarina State, Brazil

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Author(s):
Chaiana Esmeraldino Mendes Marcon [1] ; Karoline Rodrigues Campos [2] ; Gabriela Bassi da Silva [3] ; Fabiana Schuelter-Trevisol [4] ; Aline Daiane Schlindwein [5] ; Daisson José Trevisol [6] ; Adele Caterino-de-Araujo [7]
Total Authors: 7
Affiliation:
[1] Universidade do Sul de Santa Catarina. Programa de Pós-Graduação em Ciências da Saúde - Brasil
[2] Secretaria de Estado da Saúde de São Paulo. Coordenadoria de Controle de Doença. Instituto Adolfo Lutz - Brasil
[3] Secretaria de Estado da Saúde de São Paulo. Coordenadoria de Controle de Doença. Instituto Adolfo Lutz - Brasil
[4] Universidade do Sul de Santa Catarina. Programa de Pós-Graduação em Ciências da Saúde - Brasil
[5] Universidade do Sul de Santa Catarina. Programa de Pós-Graduação em Ciências da Saúde - Brasil
[6] Universidade do Sul de Santa Catarina. Programa de Pós-Graduação em Ciências da Saúde - Brasil
[7] Secretaria de Estado da Saúde de São Paulo. Coordenadoria de Controle de Doença. Instituto Adolfo Lutz - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Revista do Instituto de Medicina Tropical de São Paulo; v. 61, 2019-10-10.
Abstract

ABSTRACT Santa Catarina is a Brazilian State that has reported the lowest prevalence of human T-cell lymphotropic viruses (HTLV-1/2) in blood donors (0.04%). Although it presents ports, airports and roads that facilitate the entrance and dissemination of new infectious agents, no information exists concerning the HTLV-1/2 infections in HIV/AIDS patients. This study searched for HTLV-1/2 antibodies in plasma samples of 625 HIV/AIDS patients from the municipality of Tubarao (Southern Santa Catarina), and disclosed 1.1% of positivity (0.48% HTLV-1, 0.48% HTLV-2 and 0.16% untypeable HTLV), and a positive correlation with the male sex (OR 4.16) and intravenous drug use (OR 35.18). Although the percentage of 1.1% appears to be low, it is 27.5 times higher than the percentage detected in blood donors. Since HTLV-1 and HTLV-2 are circulating in HIV-infected individuals in Southern Santa Catarina, and these retroviruses could cause a differently impact on the HIV/AIDS outcomes, the surveillance of HTLV-1/2 is necessary, and it could support public health policies in preventing the transmission and dissemination of these viruses in this State. (AU)

FAPESP's process: 16/03654-0 - Host and virus genetic markers that influenced the course of the HIV-1, HIV-1/HTLV-1 and HIV-1/HTLV-2 coinfections
Grantee:Adele Caterino de Araújo
Support Opportunities: Regular Research Grants