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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Intratubular decontamination ability and physicochemical properties of calcium hydroxide pastes

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Pereira, Thais Cristina [1] ; da Silva Munhoz Vasconcelos, Layla Reginna [1] ; Zardin Graeff, Marcia Sirlene [2] ; Marcucci Ribeiro, Maria Cristina [3] ; Hungaro Duarte, Marco Antonio [1] ; de Andrade, Flaviana Bombarda [1]
Total Authors: 6
[1] Univ Sao Paulo, Bauru Sch Dent, Dept Operat Dent Endodont & Dent Mat, 9-75 Alameda Dr Octavio Pinheiro Brisola, BR-17012901 Bauru, SP - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, 9-75 Alameda Dr Octavio Pinheiro Brisola, BR-17012901 Bauru, SP - Brazil
[3] Univ Bandeirante Sao Paulo, 1245 Guilherme Giorgi Ave, Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: CLINICAL ORAL INVESTIGATIONS; v. 23, n. 3, p. 1253-1262, MAR 2019.
Web of Science Citations: 3

ObjectiveThis in vitro study compared the penetration, pH, calcium ion release, solubility, and intradentinal decontamination capacity of calcium hydroxide (CH) pastes with different vehicles and additives.Materials and methodsInfected standard bovine dentine contaminated with Enterococcus faecalis were treated with propolis extract, chlorhexidine, and camphorated paramonochlorophenol (CPMC) loaded in CH paste for the bacterial viability evaluation made by confocal laser scanning microscopy (CLSM) and microbiological culture. Beside this, 50 acrylic teeth were filled with the previously mentioned pastes to evaluate the pH and calcium ion release (pHmeter and atomic absorption spectrophotometer at time intervals of 7, 15, and 30days) and solubility (micro-computed tomographic imaging before and after 15days).ResultsAfter treatment, all samples decreased intra-dentinal contamination, specially, the CH paste with CPMC. There was no statistically significant difference between the groups when evaluating the intra-canal paste penetration. In the pH measurements, CH with distilled water showed the smallest pH values. Regardless the solubility percentage of the pastes, the paste of CH+PG presented the highest values.ConclusionThe vehicles and additives tested may increase CH antimicrobial effect, but with small differences. In general, all CH pastes tested here were effective in reducing Enterococcus faecalis and were similar in the penetration, pH, calcium ion release, and solubility of calcium hydroxide when compared to distilled water.Clinical relevanceThe use of calcium hydroxide pastes as intracanal medication with an aqueous or viscous vehicle, as propylene glycol, can be useful, since all formulations of the tested pastes resulted in great bacterial reduction inside root canals. (AU)

FAPESP's process: 13/26120-2 - Intra-tubular desinfection of bovine teeth contamined with calcium hydroxide pastes associated with different vehicles
Grantee:Thais Cristina Pereira
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 10/20186-3 - Adherence factors and biofilms generated by root canal microorganisms
Grantee:Flaviana Bombarda de Andrade
Support Opportunities: Regular Research Grants