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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Proteome analysis of the salivary pellicle formed on titanium alloys containing niobium and zirconium

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Pantaroto, Heloisa Navarro [1] ; Amorim, Karina Pintaudi [1] ; Cordeiro, Jairo Matozinho [1] ; Souza, Joao Gabriel S. [1] ; Ricomini-Filho, Antonio Pedro [2] ; Rangel, Elidiane C. [3, 4] ; Ribeiro, Ana Lucia R. [5] ; Vaz, Luis Geraldo [6] ; Barao, Valentim A. R. [1]
Total Authors: 9
[1] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Prosthodont & Periodontol, Sao Paulo - Brazil
[2] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Physiol Sci, Sao Paulo - Brazil
[3] Univ Estadual Paulista, Engn Coll, Lab Technol Plasmas, Sao Paulo - Brazil
[4] Fac Ciencias Tocantins FACIT, Araguaina, Tocantins - Brazil
[5] Inst Tocantinense Presidente Antonio Carlos FAHES, Fac Ciencias Humanas Econ & Saude Araguaina, Araguaina, Tocantins - Brazil
[6] Univ Estadual Paulista, Dept Dent Mat & Prosthodont, Araraquara Dent Sch, Sao Paulo - Brazil
Total Affiliations: 6
Document type: Journal article
Source: BIOFOULING; v. 35, n. 2 MAR 2019.
Web of Science Citations: 1

The chemical composition of biomaterials can drive their biological responses; therefore, this in vitro study aimed to evaluate the proteomic profile of the salivary pellicle formed on titanium (Ti) alloys containing niobium (Nb) and zirconium (Zr). The experimental groups consisted of Ti35NbxZr (x=5 and 10wt%) alloys, and commercially pure titanium (cpTi); titanium aluminium vanadium (Ti6Al4V) alloys were used as controls. The physical and chemical characteristics of the Ti materials were analysed. The proteomic profile was evaluated by liquid chromatography coupled with tandem mass spectrometry. Bacterial adhesion (2h) of mixed species (Streptococcus sanguinis and Actinomyces naeslundii) was investigated as colony-forming units (n=6). This paper reports the finding that salivary pellicle composition can be modulated by the composition of the Ti material. The Ti35NbxZr group showed a significant ability to adsorb proteins from saliva, which can favour interactions with cells and compatibility with the body. (AU)

FAPESP's process: 16/11610-2 - Surface characterization and bacterial colonization of Ti-Nb-Zr experimental ternary alloy for dental implants
Grantee:Karina Pintaudi Amorim
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 14/26853-2 - Structural, mechanical, chemical and electrochemical characterization of experimental titanium alloys for dental implants
Grantee:Jairo Matozinho Cordeiro
Support type: Scholarships in Brazil - Master
FAPESP's process: 16/11470-6 - Magnetron sputtering deposition of tantalum oxide (Ta2O5) films onto titanium surface for biomedical applications: electrochemical behavior, biocompatibility and microbiologic analysis
Grantee:Valentim Adelino Ricardo Barão
Support type: Regular Research Grants