Pantaroto, Heloisa Navarro
Amorim, Karina Pintaudi
Cordeiro, Jairo Matozinho
Souza, Joao Gabriel S.
Ricomini-Filho, Antonio Pedro
Rangel, Elidiane C.
Ribeiro, Ana Lucia R.
Vaz, Luis Geraldo
Barao, Valentim A. R.
Total Authors: 9
 Univ Estadual Campinas, Piracicaba Dent Sch, Dept Prosthodont & Periodontol, Sao Paulo - Brazil
 Univ Estadual Campinas, Piracicaba Dent Sch, Dept Physiol Sci, Sao Paulo - Brazil
 Univ Estadual Paulista, Engn Coll, Lab Technol Plasmas, Sao Paulo - Brazil
 Fac Ciencias Tocantins FACIT, Araguaina, Tocantins - Brazil
 Inst Tocantinense Presidente Antonio Carlos FAHES, Fac Ciencias Humanas Econ & Saude Araguaina, Araguaina, Tocantins - Brazil
 Univ Estadual Paulista, Dept Dent Mat & Prosthodont, Araraquara Dent Sch, Sao Paulo - Brazil
Total Affiliations: 6
Web of Science Citations:
The chemical composition of biomaterials can drive their biological responses; therefore, this in vitro study aimed to evaluate the proteomic profile of the salivary pellicle formed on titanium (Ti) alloys containing niobium (Nb) and zirconium (Zr). The experimental groups consisted of Ti35NbxZr (x=5 and 10wt%) alloys, and commercially pure titanium (cpTi); titanium aluminium vanadium (Ti6Al4V) alloys were used as controls. The physical and chemical characteristics of the Ti materials were analysed. The proteomic profile was evaluated by liquid chromatography coupled with tandem mass spectrometry. Bacterial adhesion (2h) of mixed species (Streptococcus sanguinis and Actinomyces naeslundii) was investigated as colony-forming units (n=6). This paper reports the finding that salivary pellicle composition can be modulated by the composition of the Ti material. The Ti35NbxZr group showed a significant ability to adsorb proteins from saliva, which can favour interactions with cells and compatibility with the body. (AU)