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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Lactobacillus species increase the survival of Galleria mellonella infected with Candida albicans and non-albicans Candida clinical isolates

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Santos, Rafaella Braga [1] ; Scorzoni, Liliana [1] ; Namba, Andressa Mayumi [1] ; Rossoni, Rodnei Dennis [1] ; Cardoso Jorge, Antonio Olavo [1] ; Junqueira, Juliana Campos [1]
Total Authors: 6
[1] Sao Paulo State Univ Unesp, Dept Biosci & Oral Diag, Inst Sci & Technol, Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Medical Mycology; v. 57, n. 3, p. 391-394, APR 2019.
Web of Science Citations: 4

Investigation into new therapeutic strategies, such as the use of bacterial isolates with probiotic characteristics, has increased in importance due to the high incidence of Candida albicans and non-albicans Candida infections. This study evaluates Lactobacillus paracasei, Lactobacillus fermentum and Lactobacillus rhamnosus strains as prophylactic and therapeutic agents against infection caused by Candida albicans, Candida glabrata, Candida krusei, and Candida tropicalis in a Galleria mellonella model. Prophylactic treatment provided greater benefits during Candida spp. infection, increasing G. mellonella survival, compared to therapeutic treatment. This study demonstrated that the different Lactobacillus species are potent prophylactic agents of Candida species infection. (AU)

FAPESP's process: 15/09770-9 - Isolation and characterization of Lactobacillus spp. from oral cavity and its probiotic action in Candida albicans and Streptococcus mutans
Grantee:Juliana Campos Junqueira
Support Opportunities: Regular Research Grants