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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Size Control of Carbon Spherical Shells for Sensitive Detection of Paracetamol in Sweat, Saliva, and Urine

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Campos, Anderson M. [1] ; Raymundo-Pereira, Paulo A. [2] ; Mendonca, Camila D. [1] ; Calegaro, Marcelo L. [1] ; Machado, Sergio A. S. [1] ; Oliveira, Jr., Osvaldo N. [2]
Total Authors: 6
[1] Univ Sao Paulo, Sao Carlos Inst Chem, BR-13566590 Sao Paulo - Brazil
[2] Univ Sao Paulo, Sao Carlos Inst Phys, BR-13566590 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: ACS APPLIED NANO MATERIALS; v. 1, n. 2, p. 654-661, FEB 2018.
Web of Science Citations: 9

We report on a facile strategy for separating carbon spherical shells (CSS) using centrifugation, with which shells were produced with diameter varying from 400 to 500 nm according to scanning and transmission electron microscopies. The shells were made of 79% carbon and 21% oxygen, and their surface was functionalized with carbonyl and hydroxyl groups. The CSS could form a homogeneous film on a glassy carbon (GC) electrode surface and be used in a sensing platform. In electroanalytical experiments, the sensitivity of the GC/CSS electrode for paracetamol increased with decreasing size of CSS. For 400 nm CSS, the sensitivity was 0.02 mu A mu mol(-1) L, and the limit of detection and quantification in sweat, saliva, and urine samples was 120 and 400, 286 and 470, and 584 and 530 nmol L-1, respectively, which represents the highest performance among carbon-based sensors found in the literature. The GC/CSS electrodes were stable, robust against typical interferents, and allowed detection of paracetamol in sweat, saliva, and urine samples with a performance indistinguishable from conventional high-performance liquid chromatography. (AU)

FAPESP's process: 16/01919-6 - Design and fabrication of nanostructured flexible devices for biomarkers detection
Grantee:Paulo Augusto Raymundo Pereira
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 14/05197-0 - Development of electrochemical sensors based in mesoporous sílica containing graphene for analysis of bisphenol A
Grantee:Anderson Massahiro de Campos
Support Opportunities: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 13/14262-7 - Nanostructured films from biologically-relevant materials
Grantee:Osvaldo Novais de Oliveira Junior
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 16/12759-0 - Development of an advanced electroanalytical methodology for quantification of the hormones 17²-estradiol and 17±-etinilestradiol in supply water samples using electrodes modified with graphene, gold nanoparticles and quantum dots
Grantee:Sergio Antonio Spinola Machado
Support Opportunities: Regular Research Grants
FAPESP's process: 12/17689-9 - Preparation and characterization of bifunctional-nanostructured surfaces of Au-Pt obtained via templates for application in sensors and biosensors
Grantee:Paulo Augusto Raymundo Pereira
Support Opportunities: Scholarships in Brazil - Doctorate