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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Pigments in an iridescent bacterium, Cellulophaga fucicola, isolated from Antarctica

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Author(s):
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Silva, Tiago R. [1, 2] ; Canela-Garayoa, Ramon [3] ; Eras, Jordi [3] ; Rodrigues, Marili V. N. [4] ; dos Santos, Fabio N. [5] ; Eberlin, Marcos N. [5] ; Neri-Numa, Iramaia A. [6] ; Pastore, Glaucia M. [6] ; Tavares, Renata S. N. [7] ; Debonsi, Hosana M. [7] ; Cordeiro, Lorena R. G. [7] ; Rosa, Luiz H. [8] ; Oliveira, Valeria M. [2]
Total Authors: 13
Affiliation:
[1] Campinas State Univ UNICAMP, Inst Biol, POB 6109, Campinas, SP - Brazil
[2] Univ Estadual Campinas, Div Microbial Resources, Chem Biol & Agr Pluridisciplinary Res Ctr CPQBA, Campinas, SP - Brazil
[3] Univ Lleida, ETSEA, Dept Chem, Agrotecnio Ctr, Lleida - Spain
[4] Univ Estadual Campinas, Dept Organ Chem, Chem Biol & Agr Pluridisciplinary Res Ctr CPQBA, Campinas, SP - Brazil
[5] Campinas State Univ UNICAMP, ThoMSon Mass Spectrometry Lab, Campinas, SP - Brazil
[6] Univ Campinas UNICAMP, Dept Food Sci, Sch Food Engn, Campinas, SP - Brazil
[7] Univ Sao Paulo, Sch Pharmaceut Sci Ribeirao Preto, Ribeirao Preto, SP - Brazil
[8] Univ Fed Minas Gerais, Dept Microbiol, Inst Biol Sci, Belo Horizonte, MG - Brazil
Total Affiliations: 8
Document type: Journal article
Source: ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY; v. 112, n. 3, p. 479-490, MAR 2019.
Web of Science Citations: 1
Abstract

An iridescent yellow pigmented bacterium isolated from the Antarctic continent, named Cellulophaga fucicola strain 416, was found to be able to tolerate UV-B radiation. Its crude pigment extract was tested for antioxidant capacity, UV light stability and phototoxicity profile against murine fibroblast lines. The pigments were further isolated and chemically identified by ultra-high-performance liquid chromatography with photodiode array and mass spectrometry detectors. The results showed that the pigment extract presented weak stability under exposure to UV light, a phototoxic profile in the 3t3 Neutral Red Uptake test and a very high antioxidant activity, suggesting that it could be used as food and feed colourants. Zeaxanthin and two isomers of zeaxanthin, -cryptoxanthin and -carotene, were identified using a C18 column. These five carotenoids were the major pigments isolated from C. fucicola 416. In conclusion, the identification of pigments produced by the bacterial strain under study may help us understand how bacteria thrive in high UV and cold environments, and opens avenues for further biotechnological application towards a more sustainable and environmentally friendly way of pigment exploitation. (AU)

FAPESP's process: 16/05640-6 - Multi-omics applied to the understanding and exploitation of Antarctic microbiomes
Grantee:Valeria Maia Merzel
Support type: Regular Research Grants
FAPESP's process: 17/21790-0 - Chemical characterization of pigments of biotechnological interest from bacteria isolated from Antarctica
Grantee:Tiago Rodrigues e Silva
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 14/17936-1 - Microbial prospecting for antibiotics and pigments from bacteria isolated from Antarctica.
Grantee:Tiago Rodrigues e Silva
Support type: Scholarships in Brazil - Doctorate