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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Gut microbiome approaches to treat obesity in humans

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Author(s):
Bianchi, Fernanda [1] ; Rocha Faria Duque, Ana Luiza [1] ; Isay Saad, Susana Marta [2, 3] ; Sivieri, Katia [1]
Total Authors: 4
Affiliation:
[1] State Univ Sao Paulo UNESP, Dept Food & Nutr, Sch Pharmaceut Sci, Araraquara, SP - Brazil
[2] Univ Sao Paulo, Dept Biochem & Pharmaceut Technol, Sao Paulo, SP - Brazil
[3] Univ Sao Paulo, Food Res Ctr, Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Review article
Source: Applied Microbiology and Biotechnology; v. 103, n. 3, p. 1081-1094, FEB 2019.
Web of Science Citations: 4
Abstract

The rising worldwide prevalence of obesity has become a major concern having many implications for the public health and the economy. It is well known that many factors such as lifestyle, increased intake of foods high in fat and sugar and a host's genetic profile can lead to obesity. Besides these factors, recent studies have pointed to the gut microbiota composition as being responsible for the development of obesity. Since then, many efforts have been made to understand the link between the gut microbiota composition and obesity, as well as the role of food ingredients, such as pro- and prebiotics, in the modulation of the gut microbiota. Studies involving the gut microbiota composition of obese individuals are however still controversial, making it difficult to treat obesity. In this sense, this mini-review deals with obesity and the relationship with gut microbiota, summarising the principal findings on gut microbiome approaches for treating obesity in humans. (AU)

FAPESP's process: 15/08228-6 - Selection and assessment of the combination between waste of tropical fruits and probiotic strains in the modulation of intestinal microbiota of obese compared to the normal weight using the simulator of the human intestinal microbial ecosystem
Grantee:Fernanda Bianchi
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 15/13965-0 - Selection and assessment of the combination between waste of tropical fruits and probiotic strains in the modulation of intestinal microbiota of obese compared to the normal weight using the simulator of the human intestinal microbial ecosystem
Grantee:Katia Sivieri
Support type: Regular Research Grants
FAPESP's process: 13/50506-8 - Bioactive components from by-products of food processing used in a symbiotic approach for improving human health and well-being (BioSyn)
Grantee:Susana Marta Isay Saad
Support type: Research Projects - Thematic Grants