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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Impact of combining acerola by-product with a probiotic strain on a gut microbiome model

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Author(s):
Bianchi, Fernanda [1] ; Lopes, Natalia Pontin [1] ; Tallarico Adorno, Maria Angela [2] ; Sakamoto, Isabel Kimiko [2] ; Genovese, Maria Ines [3] ; Isay Saad, Susana Marta [4, 5] ; Sivieri, Katia [1]
Total Authors: 7
Affiliation:
[1] State Univ Sao Paulo UNESP, Sch Pharmaceut Sci, Dept Food & Nutr, Rodovia Araraquara Jau Km 1 S-N, BR-14801902 Araraquara, SP - Brazil
[2] Univ Sao Paulo, Sch Engn Sao Carlos, Dept Hydraul & Sanitat, Sao Carlos, SP - Brazil
[3] Univ Sao Paulo, Sch Pharmaceut Sci, Dept Food & Expt Nutr, Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Biochem & Pharmaceut Technol, Sao Paulo - Brazil
[5] Univ Sao Paulo, Food Res Ctr, Sao Paulo - Brazil
Total Affiliations: 5
Document type: Journal article
Source: INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION; v. 70, n. 2, p. 182-194, FEB 17 2019.
Web of Science Citations: 1
Abstract

In this study, we first investigated the survival of three probiotic strains, individually and combined with acerola by-product during simulated gastrointestinal conditions. Next, we investigated the effects of acerola by-product combined with Bifidobacterium longum BB-46 on a gut microbiota model (SHIME (R)). Chemical composition, total phenolic compounds, antioxidant activity of the acerola by-product and microbial counts, denaturing gradient gel electrophoresis (DGGE), ammonium ions () and short-chain fatty acids (SCFAs) analysis of the SHIME (R) samples were performed. Acerola by-product revealed high protein and fibre, reduced lipid contents, and showed to be an excellent source of total phenolic compounds with high in vitro antioxidant activity. A decreased amount of in the ascending colon and an increase (p < .05) in SCFAs were observed in the three regions of colon during treatment with BB-46 and acerola by-product. BB-46 combined with acerola by-product showed positive effects on the gut microbiota metabolism in SHIME (R) model. (AU)

FAPESP's process: 15/08228-6 - Selection and assessment of the combination between waste of tropical fruits and probiotic strains in the modulation of intestinal microbiota of obese compared to the normal weight using the simulator of the human intestinal microbial ecosystem
Grantee:Fernanda Bianchi
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 13/50506-8 - Bioactive components from by-products of food processing used in a symbiotic approach for improving human health and well-being (BioSyn)
Grantee:Susana Marta Isay Saad
Support type: Research Projects - Thematic Grants
FAPESP's process: 15/13965-0 - Selection and assessment of the combination between waste of tropical fruits and probiotic strains in the modulation of intestinal microbiota of obese compared to the normal weight using the simulator of the human intestinal microbial ecosystem
Grantee:Katia Sivieri
Support type: Regular Research Grants