Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis

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Author(s):	Pedroso, Tahisa Marcela ^[1] ; Van Schepdael, Ann ^[2] ; Nunes Salgado, Herida Regina ^[1] Total Authors: 3
Affiliation:	^[1] Univ Estadual Paulista, UNESP, Fac Ciencias Farmaceut, Araraquara, SP - Brazil ^[2] Univ Leuven, KU Leuven, Dept Pharmaceut & Pharmacol Sci, Pharmaceut Anal, Leuven - Belgium Total Affiliations: 2
Document type:	Journal article
Source:	INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY; 2019.
Web of Science Citations:	0
Abstract
An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10mM pH 7 and 15kV voltage, in the concentration range of 70 to 120gmL(-1). Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x - 24495 with a R-2 = 0.9994. Thus, we propose a routine analysis method that meets the principles of green analytical chemistry for the routine analysis of ertapenem sodium by capillary electrophoresis. (AU)

FAPESP's process:	09/14825-6 - PHARMACEUTICAL ANALISIS OF DRUGS AND MEDICINES: CEFUROXIME, TEICOPLANIN AND AZUMOLENE
Grantee:	Hérida Regina Nunes Salgado
Support Opportunities:	Regular Research Grants


FAPESP's process:	13/12959-0 - DEVELOPMENT AND VALIDATION OF ANALYTICAL METHODS FOR CHARACTERIZATION AND QUANTIFICATION OF ERTAPENEM SODIUM IN LYOPHILIZED POWDER FOR INJECTABLE SOLUTION
Grantee:	Tahisa Marcela Pedroso
Support Opportunities:	Scholarships in Brazil - Doctorate