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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

White tea intake interferes with the expression of angiogenic factors in the corpora lutea of superovulated rats

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Author(s):
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Santos, Francislaine Anelize Garcia [1] ; Freire, Samuel Aparecido [2] ; Vieira, Deyvid Parreira [2] ; Papa, Paula de Carvalho [1] ; de Barros, Gabriela Fernandes [2] ; Castilho, Calie [2] ; Guaberto, Luciana Machado [2] ; Arantes de Souza, Lilian Francisco [2] ; Laposy, Cecilia Braga [2] ; Barilli Nogueira, Rosa Maria [2] ; Santos, Aline de Oliveira [2] ; Giometti, Ines Cristina [2]
Total Authors: 12
Affiliation:
[1] Univ Sao Paulo, Fac Med Vet & Zootecnia, Av Prof Dr, Orlando Marques Paiva 87, BR-05508270 Sao Paulo, SP - Brazil
[2] Univ Oeste Paulista UNOESTE, Campus II, Rod Raposo Tavares, Km 572, BR-19067175 Presidente Prudente, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY; v. 53, n. 7, p. 1666-1671, JUL 2018.
Web of Science Citations: 1
Abstract

White tea derived from the Camellia sinensis (L.) plant has anticancer effects. Its main catechin decreases the gene expression of Vegf in tumours. However, VEGF is also the angiogenic factor of the reproductive organs. In this study, Wistar rats were divided into the following groups (n=30): the control group (CT), which received water, and the white tea intake group (WT), for 3months. At the end of every month, the corpora lutea (CL) of ten rats were removed to evaluate the gene expression of Vegf and its receptors (Flt-1 and Kdr). White tea increased the relative mRNA abundance of Vegf (CT=0.95 +/- 0.06 and WT=2.13 +/- 0.19), Kdr (CT=0.88 +/- 0.06 and WT=1.94 +/- 0.32) and Flt-1 (CT=0.94 +/- 0.06 and WT=2.11 +/- 0.22) in CL (P<0.05). White tea increased angiogenic-related genes in rat CL but did not alter the number of rat CL. (AU)

FAPESP's process: 10/20583-2 - Influence of green tea from the Camellia sinensis plant in the reproduction of superovulated Wistar rats and in the gene expression of vascular endothelial growth factor (VEGF) of corpus luteum
Grantee:Ines Cristina Giometti Ceda
Support type: Regular Research Grants
FAPESP's process: 10/20100-1 - Influence of White tea from Camellia sinensis plant in the reproduction of superovulated Wistar rats.
Grantee:Samuel Aparecido Freire
Support type: Scholarships in Brazil - Scientific Initiation