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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Comparison between body mass index and a body shape index with adiponectin/leptin ratio and markers of glucose metabolism among

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Giudici, Kelly Virecoulon [1] ; Martini, Ligia Araujo [1]
Total Authors: 2
[1] Univ Sao Paulo, Sch Publ Hlth, Nutr Dept, Ave Doutor Arnaldo 715, BR-01246904 Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: ANNALS OF HUMAN BIOLOGY; v. 44, n. 6, p. 489-494, 2017.
Web of Science Citations: 4

Background: Besides body mass index (BMI), new parameters have been developed to classify individual body shape. Aim: To investigate the relationship between BMI, waist circumference (WC), a body shape index (ABSI) and ABSI-adolescents among adolescents and verify which would better predict lower adiponectin/ leptin (A/L) ratio and disturbances on glucose metabolism. Subjects and methods: A cross-sectional study with 197 Brazilian adolescents of 14-18 years. Serum leptin, adiponectin, glucose and insulin were measured. A/L ratio, ABSI, ABSI-adolescents, BMI, homeostasis model assessment estimates of insulin resistance (HOMA-IR) and beta-cell function (HOMA-b) and the quantitative insulin sensitivity check index (QUICKI) were calculated. Results: ABSI-adolescents positively correlated with WC (r = 0.83, p < 0.0001) and BMI (r = 0.66, p< 0.0001), but stronger correlations were observed between WC and BMI (r = 0.95, p < 0.0001). ABSIadolescents, BMI and WC negatively correlated with A/L ratio (all p < 0.0001). The correlation between BMI and A/L ratio was the strongest (r = -0.63, p < 0.001). A/L ratio, BMI, WC and ABSI-adolescents correlated with markers of glucose metabolism (all p < 0.0001) and the strongest correlation was observed with BMI (QUICKI: r = -0.75; HOMA-IR: r = 0.76; HOMA-beta: r = 0.77; insulin: r = 0.79). Associations were confirmed by linear regression analysis, adjusted for sex and age. Conclusions: ABSI-adolescents, but not ABSI, was related to A/L ratio and to markers of glucose metabolism, but not more strongly than BMI and WC. (AU)

FAPESP's process: 12/11061-8 - Adipose tissue and bone: metabolic pathway between vitamin D, osteocalcin and adipokines in adolescents
Grantee:Lígia Araújo Martini
Support type: Regular Research Grants
FAPESP's process: 11/22768-2 - Relationship between fat mass and bone: metabolic interaction between vitamin D, vitamin D receptor genotype, osteocalcin and leptin in adolescentes
Grantee:Kelly Virecoulon Giudici
Support type: Scholarships in Brazil - Doctorate (Direct)