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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Ureaplasma urealyticum and U. parvum in sexually active women attending public health clinics in Brazil

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Author(s):
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Lobao, T. N. ; Campos, G. B. ; Selis, N. N. ; Amorim, A. T. ; Souza, S. G. ; Mafra, S. S. ; Pereira, L. S. ; Dos Santos, D. B. ; Figueiredo, T. B. ; Marques, L. M. ; Timenetsky, J.
Total Authors: 11
Document type: Journal article
Source: EPIDEMIOLOGY AND INFECTION; v. 145, n. 11, p. 2341-2351, AUG 2017.
Web of Science Citations: 3
Abstract

Ureaplasma urealyticum and U. parvum have been associated with genital infections. The purpose of this study was to detect the presence of ureaplasmas and other sexually transmitted infections in sexually active women from Brazil and relate these data to demographic and sexual health, and cytokines IL-6 and IL-1 ss. Samples of cervical swab of 302 women were examined at the Family Health Units in Vitoria da Conquista. The frequency of detection by conventional PCR was 76.2% for Mollicutes. In qPCR, the frequency found was 16.6% for U. urealyticum and 60.6% U. parvum and the bacterial load of these microorganisms was not significantly associated with signs and symptoms of genital infection. The frequency found for Trichomonas vaginalis, Neisseria gonorrhoeae, Gardnerella vaginalis and Chlamydia trachomatis was 3.0%, 21.5%, 42.4% and 1.7%, respectively. Higher levels of IL-1 beta were associated with control women colonized by U. urealyticum and U. parvum. Increased levels of IL-6 were associated with women who exhibited U. parvum. Sexually active women, with more than one sexual partner in the last 3 months, living in a rural area were associated with increased odds of certain U. parvum serovar infection. (AU)

FAPESP's process: 11/10138-4 - Detection of mollicutes in the female urogenital tract and its relation to genetic polymorphisms and expression of cytokines in women of Vitoria da Conquista, BA
Grantee:Jorge Timenetsky
Support Opportunities: Regular Research Grants