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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Insights into Penicillium brasilianum Secondary Metabolism and Its Biotechnological Potential

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Bazioli, Jaqueline Moraes ; Amaral, Luciana Da Silva ; Fill, Taicia Pacheco ; Rodrigues-Filho, Edson
Total Authors: 4
Document type: Review article
Source: Molecules; v. 22, n. 6 JUN 2017.
Web of Science Citations: 5

Over the past few years Penicillium brasilianum has been isolated from many different environmental sources as soil isolates, plant endophytes and onion pathogen. All investigated strains share a great ability to produce bioactive secondary metabolites. Different authors have investigated this great capability and here we summarize the metabolic potential and the biological activities related to P. brasilianum's metabolites with diverse structures. They include secondary metabolites of an alkaloid nature, i.e., 2,5-diketopiperazines, cyclodepsipeptides, meroterpenoids and polyketides. Penicillium brasilianum is also described as a great source of enzymes with biotechnological application potential, which is also highlighted in this review. Additionally, this review will focus on several aspects of Penicillium brasilianum and interesting genomic insights. (AU)

FAPESP's process: 15/10384-6 - Biosynthetic studies involving bottom-up approaches of polyketides produced by Penicillium species
Grantee:Taicia Pacheco Fill
Support Opportunities: Regular Research Grants