| Full text | |
| Author(s): |
Basso, F. G.
;
Hebling, J.
;
Marcelo, C. L.
;
Costa, C. A. de Souza
;
Feinberg, S. E.
Total Authors: 5
|
| Document type: | Journal article |
| Source: | BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY; v. 55, n. 3, p. 308-311, APR 2017. |
| Web of Science Citations: | 0 |
| Abstract | |
We evaluated the suitability of a porcine acellular dermal matrix for the development of a 3-dimensional oral mucosal equivalent using an exvivo-produced oral mucosal equivalent (EVPOME). Oral keratinocytes were seeded in a submerged model, and then in an air-liquid interphase model, using Transwell((R)) inserts. EVPOME showed good cell viability and increased glucose consumption over time. Histological evaluation showed that stratified differentiated epithelium had formed in all matrices. (C) 2016 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. (AU) | |
| FAPESP's process: | 12/17947-8 - EFFECTS OF LOW-LEVEL LASER THERAPY ON INFLAMMATORY CYTOKINES EXPRESSION ON ORAL MUCOSITIS |
| Grantee: | Fernanda Gonçalves Basso |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 14/06057-7 - Development of a 3D oral mucosa model for in vitro studies |
| Grantee: | Fernanda Gonçalves Basso |
| Support Opportunities: | Scholarships abroad - Research Internship - Post-doctor |
| FAPESP's process: | 13/05879-0 - Effect of low-level laser therapy and growth factors on gingival fibroblasts activity of young and aged patients |
| Grantee: | Carlos Alberto de Souza Costa |
| Support Opportunities: | Regular Research Grants |