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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates

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Author(s):
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Shaw-Saliba, Kathryn ; Clarke, David ; Santos, Jorge M. ; Menezes, Maria Jose ; Lim, Caeul ; Mascarenhas, Anjali ; Chery, Laura ; Gomes, Edwin ; March, Sandra ; Bhatia, Sangeeta N. ; Rathod, Pradipsinh K. ; Ferreira, Marcelo U. ; Catteruccia, Flaminia ; Duraisingh, Manoj T.
Total Authors: 14
Document type: Journal article
Source: International Journal for Parasitology; v. 46, n. 11, p. 679-683, OCT 2016.
Web of Science Citations: 5
Abstract

Plasmodium vivax is the most geographically widespread malaria parasite. Unique features of transmission biology complicate P. vivax control. Interventions targeting transmission are required for malaria eradication. In the absence of an in vitro culture, transmission studies rely on live isolates from non-human primates or endemic regions. Here, we demonstrate P. vivax gametocytes from both India and Brazil are stable during cryopreservation. Importantly, cryopreserved gametocytes from Brazil were capable of infecting three anopheline mosquito species in feedings done in the United States. These findings create new opportunities for transmission studies in diverse locales. (C) 2016 Australian Society for Parasitology. Published by Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 09/52729-9 - Determinants and consequences of asymptomatic carriage of malaria parasites: population-based studies in rural Brazilian Amazonia
Grantee:Marcelo Urbano Ferreira
Support Opportunities: Regular Research Grants