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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Straightforward synthesis and antioxidant studies of chalcogenoaziridines

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Author(s):
Borges, Rodrigo ; Andrade, Floyd C. D. ; Schwab, Ricardo S. ; Sousa, Fernanda S. S. ; de Souza, Maurice Neto ; Savegnago, Lucielli ; Schneider, Paulo H.
Total Authors: 7
Document type: Journal article
Source: Tetrahedron Letters; v. 57, n. 31, p. 3501-3504, AUG 3 2016.
Web of Science Citations: 4
Abstract

Herein we reported the synthesis of chalcogenoaziridines through the introduction of the organoselenium moiety in the aziridine framework through the nucleophilic substitution of the OTs leaving group. In addition, the antioxidant activity, as reflected by free radical scavenging, was also evaluated. The new seleno aziridine 6a showed more effective antioxidant compared to other compounds. These findings also suggest that seleno aziridine 6a is a promising antioxidant and that its activity is not influenced by the presence of the substituents attached into the aromatic ring. (C) 2016 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 13/06558-3 - Asymmetric catalysis: preparation of chiral alcohols and their derivatives from highly functionalized organozinc reagents and application of new chiral ligands supported on magnetic nanoparticles
Grantee:Ricardo Samuel Schwab
Support Opportunities: Regular Research Grants