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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cardioprotective Properties of Aerobic and Resistance Training Against Myocardial Infarction

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Author(s):
Barboza, C. A. [1] ; Souza, G. I. H. [1] ; Oliveira, J. C. M. F. [1] ; Silva, L. M. [1] ; Mostarda, C. T. [2] ; Dourado, P. M. M. [3] ; Oyama, L. M. [4] ; Lira, F. S. [5] ; Irigoyen, M. C. [3] ; Rodrigues, B. [6]
Total Authors: 10
Affiliation:
[1] Univ Sao Judas Tadeu, Human Movement Lab, Sao Paulo, SP - Brazil
[2] Univ Fed Maranhao, Hosp Materno Infantil, Sao Luis, MA - Brazil
[3] Univ Sao Paulo, Sch Med, Inst Heart, Sao Paulo, SP - Brazil
[4] Univ Fed Sao Paulo, Dept Fisiol, Sao Paulo, SP - Brazil
[5] Univ Estadual Paulista, Exercise & Immunometab Res Grp, Dept Phys Educ, Presidente Prudente, SP - Brazil
[6] Univ Campinas UNICAMP, Fac Phys Educ, Av Erico Verissimo 701, Cidade Univ, BR-13083851 Campinas, SP - Brazil
Total Affiliations: 6
Document type: Journal article
Source: INTERNATIONAL JOURNAL OF SPORTS MEDICINE; v. 37, n. 6, p. 421-430, JUN 2016.
Web of Science Citations: 5
Abstract

We evaluated the effects of aerobic and resistance exercise training on ventricular morphometry and function, physical capacity, autonomic function, as well as on ventricular inflammatory status in trained rats prior to myocardial infarction. Male Wistar rats were divided into the following groups: sedentary+Sham, sedentary+myocardial infarction, aerobic trained+myocardial infarction, and resistance trained+myocardial infarction. Sham and myocardial infarction were performed after training periods. In the days following the surgeries, evaluations were performed. Aerobic training prevents aerobic (to a greater extent) and resistance capacity impairments, ventricular dysfunction, baroreflex sensitivity and autonomic disorders (vagal tonus decrease and sympathetic tonus increase) triggered by myocardial infarction. Resistance training was able to prevent negative changes to aerobic and resistance capacity (to a greater extent) but not to ventricular dysfunction, and it prevented cardiovascular sympathetic increments. Additionally, both types of training reduced left ventricle inflammatory cytokine concentration. Our results suggest that aerobic and, for the first time, dynamic resistance training were able to reduce sympathetic tonus to the heart and vessels, as well as preventing the increase in pro-inflammatory cytokine concentrations in the left ventricle of trained groups. These data emphasizes the positive effects of aerobic and dynamic resistance training on the prevention of the negative changes triggered by myocardial infarction. (AU)

FAPESP's process: 13/14788-9 - Effects of exercise training and cholinergic stimulation with pyridostigmine bromide before and after myocardial infarction: role on cardiac and autonomic function, and inflammatory profile
Grantee:Bruno Rodrigues
Support Opportunities: Regular Research Grants
FAPESP's process: 14/06669-2 - Aerobic and resistance exercise training associated with cholinergic stimulation by pyridostigmine bromide previously to myocardial infarction in rats: role on cardiac and autonomic function, and in inflammatory profile
Grantee:Catarina de Andrade Barboza
Support Opportunities: Scholarships in Brazil - Doctorate