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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

High prevalence of hepatitis E virus antibodies among blood donors in Southern Brazil

Full text
Author(s):
Passos-Castilho, Ana Maria [1] ; de Sena, Anne [2, 1] ; Geraldo, Alexandre [3, 4] ; Spada, Celso [3] ; Granato, Celso F. H. [2, 1]
Total Authors: 5
Affiliation:
[1] Univ Fed Sao Paulo, Div Infect Dis, 781 Pedro Toledo St, BR-04039032 Sao Paulo - Brazil
[2] Fleury SA Grp, Sao Paulo - Brazil
[3] Univ Fed Santa Catarina, Dept Clin Anal, Florianopolis, SC - Brazil
[4] HEMOSC Santa Catarina Hematol & Hemotherapy Ctr, Blumenau - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Journal of Medical Virology; v. 88, n. 2, p. 361-364, FEB 2016.
Web of Science Citations: 19
Abstract

Brazil has been classified as moderately endemic for hepatitis E virus (HEV) infection. However, data on the seroprevalence of HEV in this region are limited. This study evaluated the prevalence of past or present HEV infection among blood donors in the metropolitan area of Itajai Valley, Southern Brazil, a region of predominant German heritage, where cultural habits result in a high consumption of pork. Serum samples from 300 blood donors were tested in December 2014 using serological and molecular methods. Anti-HEV IgG antibodies were detected in 30 (10%) subjects, and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Only one subject had anti-HEV IgM, whereas none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG in blood donors than previously reported in Brazil. (c) 2015 Wiley Periodicals, Inc. (AU)

FAPESP's process: 12/22925-3 - Hepatitis e virus infection in immunocompromised patients: detection, viral load determination and molecular characterization
Grantee:Celso Francisco Hernandes Granato
Support Opportunities: Regular Research Grants
FAPESP's process: 13/03701-0 - Identification of lipidomic markers with diagnostic potential in hepatocellular carcinoma
Grantee:Ana Maria Passos
Support Opportunities: Scholarships in Brazil - Doctorate