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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Microevolution of Aedes aegypti

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Author(s):
Louise, Caroline [1, 2] ; Vidal, Paloma Oliveira [1, 3] ; Suesdek, Lincoln [1, 2]
Total Authors: 3
Affiliation:
[1] Inst Butantan, Lab Parasitol, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Inst Med Trop, Programa Posgrad Med Trop, Sao Paulo, SP - Brazil
[3] Univ Sao Paulo, Inst Ciencias Biomed, Programa Posgrad Biol Relacao Patogenohosp, BR-05508 Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: PLoS One; v. 10, n. 9 SEP 11 2015.
Web of Science Citations: 18
Abstract

Scientific research into the epidemiology of dengue frequently focuses on the microevolution and dispersion of the mosquito Aedes aegypti. One of the world's largest urban agglomerations infested by Ae. aegypti is the Brazilian megalopolis of Sao Paulo, where >26,900 cases of dengue were reported until June 2015. Unfortunately, the dynamics of the genetic variability of Ae. aegypti in the Sao Paulo area have not been well studied. To reduce this knowledge gap, we assessed the morphogenetic variability of a population of Ae. aegypti from a densely urbanised neighbourhood of Sao Paulo. We tested if allelic patterns could vary over a short term and if wing shape could be a predictor of the genetic variation. Over a period of 14 months, we examined the variation of genetic (microsatellites loci) and morphological (wing geometry) markers in Ae. aegypti. Polymorphisms were detected, as revealed by the variability of 20 microsatellite loci (115 alleles combined; overall F-st = 0.0358) and 18 wing landmarks (quantitative estimator Q(st) = 0.4732). These levels of polymorphism are higher than typically expected to an exotic species. Allelic frequencies of the loci changed over time and temporal variation in the wing shape was even more pronounced, permitting high reclassification levels of chronological samples. In spite of the fact that both markers underwent temporal variation, no correlation was detected between their dynamics. We concluded that microevolution was detected despite the short observational period, but the intensities of change of the markers were discrepant. Wing shape failed from predicting allelic temporal variation. Possibly, natural selection (Q(st)>F-st) or variance of expressivity of wing phenotype are involved in this discrepancy. Other possibly influential factors on microevolution of Ae. aegypti are worth searching. Additionally, the implications of the rapid evolution and high polymorphism of this mosquito vector on the efficacy of control methods have yet to be investigated. (AU)

FAPESP's process: 11/18962-8 - Microevolution of Aedes aegypti from São Paulo City
Grantee:Caroline Louise Garcia Mendes
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 10/15039-1 - Molecular and morphological characterization of Aedes aegypti populations (Diptera: Culicidae) from State of São Paulo
Grantee:Paloma Oliveira Vidal
Support type: Scholarships in Brazil - Doctorate