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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Validation of cone-beam computed tomography and magnetic resonance imaging of the porcine spine: a comparative study with multidetector computed tomography and anatomical specimens

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Costa de Freitas, Ricardo Miguel [1, 2] ; Andrade, Celi Santos [1] ; Mendes Pereira Caldas, Jose Guilherme [1] ; Kanas, Alexandre Fligelman [1] ; Cabral, Richard Halti [3] ; Tsunemi, Miriam Harumi [4] ; Cervantes Rodriguez, Hernan Joel [5] ; Rabbani, Said Rahnamaye [5]
Total Authors: 8
[1] Univ Sao Paulo, Fac Med, Inst Radiol InRad, Dept Radiol, BR-05403900 Sao Paulo, SP - Brazil
[2] Inst Canc Estado Sao Paulo, Radiol Unit, BR-01246000 Sao Paulo, SP - Brazil
[3] Univ Sao Paulo, Inst Biomed Sci, Dept Anat, BR-05508900 Sao Paulo, SP - Brazil
[4] Univ Estadual Paulista, Biosci Inst, Dept Biostat, BR-18618970 Botucatu, SP - Brazil
[5] Univ Sao Paulo, Inst Fis, Magnet Resonance Imaging Lab, BR-05508090 Sao Paulo, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: SPINE JOURNAL; v. 15, n. 5, p. 992-999, MAY 1 2015.
Web of Science Citations: 0

BACKGROUND CONTEXT: New spinal interventions or implants have been tested on ex vivo or in vivo porcine spines, as they are readily available and have been accepted as a comparable model to human cadaver spines. Imaging-guided interventional procedures of the spine are mostly based on fluoroscopy or, still, on multidetector computed tomography (MDCT). Cone-beam computed tomography (CBCT) and magnetic resonance imaging (MRI) are also available methods to guide interventional procedures. Although some MDCT data from porcine spines are available in the literature, validation of the measurements on CBCT and MRI is lacking. PURPOSE: To describe and compare the anatomical measurements accomplished with MDCT, CBCT, and MRI of lumbar porcine spines to determine if CBCT and MRI are also useful methods for experimental studies. STUDY DESIGN: An experimental descriptive-comparative study. METHODS: Sixteen anatomical measurements of an individual vertebra from six lumbar porcine spines (n=36 vertebrae) were compared with their MDCT, CBCT, and MRI equivalents. Comparisons were made for the absolute values of the parameters. RESULTS: Similarities were found in all imaging methods. Significant correlation (p<.05) was observed with all variables except those that included cartilaginous tissue from the end plates when the anatomical study was compared with the imaging methods. CONCLUSIONS: The CBCT and MRI provided imaging measurements of the lumbar porcine spines that were similar to the anatomical and MDCT data, and they can be useful for specific experimental research studies. (C) 2015 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 12/00398-1 - White Matter Evaluation with Diffusion Magnetic Resonance Imaging Techniques at High Field Strength and Multiparametric Correlation with Volumetry and Phosphorus Spectroscopy in Patients with Epilepsy and Malformations of Cortical Development
Grantee:Celi Santos Andrade
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 11/51222-8 - Evaluation of carbon dioxide thermal protection over neural structures of the spine canal of porcine models treated by computed tomography/fluoroscopy guided percutaneous vertebral cryoablation: radiological-anatomopathological correlation
Grantee:José Guilherme Mendes Pereira Caldas
Support Opportunities: Regular Research Grants