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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of the Addition of Antimicrobial Agents on Shore A Hardness and Roughness of Soft Lining Materials

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Urban, Vanessa M. [1] ; Lima, Thiago F. [2] ; Bueno, Mirian G. [2] ; Giannini, Marcelo [3] ; Arioli Filho, Joao N. [4] ; de Almeida, Ana Lucia P. F. [2] ; Neppelenbroek, Karin H. [2]
Total Authors: 7
[1] Univ Estadual Ponta Grossa, Dept Dent, Ponta Grossa - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, Dept Prosthodont, Bauru - Brazil
[3] Univ Estadual Campinas, Piracicaba Sch Dent, Dept Restorat Dent, Piracicaba - Brazil
[4] Sao Paulo State Univ, Araraquara Dent Sch, Dept Dent Mat & Prosthodont, Araraquara - Brazil
Total Affiliations: 4
Document type: Journal article
Web of Science Citations: 9

PurposeWhile the incorporation of antimicrobial agents into soft denture liners has been suggested as a reliable alternative treatment for denture stomatitis, it may affect the liner's properties. The effect of addition of antimicrobial agents for the treatment of denture stomatitis on the surface roughness and Shore A hardness of soft lining materials was evaluated. Materials and MethodsThe test groups comprised specimens (36 x 7 x 6 mm(3)) of soft materials (Softone and Trusoft) without (control) or with incorporation of drugs (nystatin, miconazole, ketoconazole, chlorhexidine diacetate, and itraconazole). Hardness (Shore A) and roughness (Ra) were evaluated after immersion of specimens (n = 10) in distilled water at 37 degrees C for 24 hours, 7 and 14 days. Data were analyzed by 3-way ANOVA/Tukey's test ( = 0.05). ResultsAfter 14 days, an increase (p < 0.05) was observed in the hardness of soft materials with time for the modified specimens, except for itraconazole. Addition of drugs increased the Softone roughness only for the addition of miconazole and chlorhexidine (p < 0.05), and did not increase the roughness of Trusoft with time. Only chlorhexidine and itraconazole altered the roughness compared to the control for each material (p < 0.05). ConclusionsThe smallest changes of hardness and roughness with time in the modified groups compared to controls were observed for itraconazole groups for both materials. (AU)

FAPESP's process: 12/11074-2 - Modification of temporary resilient liners for dentures with antimicrobial agents: in vitro and in vivo studies
Grantee:Karin Hermana Neppelenbroek
Support Opportunities: Regular Research Grants
FAPESP's process: 09/18578-3 - Effect of the incorporation of antimicrobial agents for denture stomatitis treatment of the Shore A hardness and surface roughness of resilient materials
Grantee:Thiago Freire Lima
Support Opportunities: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 10/07932-8 - Microbiological, structural, mechanical and physical evaluation of resilient materials modified by the addition of antimicrobial agents for denture stomatitis treatment
Grantee:Karin Hermana Neppelenbroek
Support Opportunities: Regular Research Grants